UID:
almafu_9959327609802883
Format:
1 online resource (xv, 323 pages) :
,
illustrations
Edition:
Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010.
ISBN:
0471692786
,
9780471692782
,
0470043407
,
9780470043400
,
0470043393
,
9780470043394
Content:
Using recent examples and important case studies, The Fundamentals of Early Clinical Drug Development: From Synthesis Design to Formulation demonstrates the central role℗¡that organic synthesis plays in the early clinical evaluation of potential drug candidates.
Note:
Reflections on process research II / Edward J.J. Grabowski -- Development and scale-up of a heterocyclic cross-coupling for the synthesis of 5-(2-(3-methyl-3H-imidazol-4-yl)thieno(3,2-b)pyridin-7-yl)amino-2-methyl-1H-indol / John A. Ragan -- Large-scale enantioselective preparation of 2E,7E, 5S,6R, 5-hydroxy-6-methyl-8-phenyl-octa-2,7-dienoic acid, a key fragment for the formal total synthesis of the anti-tumor agent cryptophycin 52 / James Aikins [and others] -- Efforts toward a commercially viable route and process to the synthesis of HIV PI GW640385X / John C. Roberts [and others] -- Development of an asymmetric synthesis of ABT-100 / Albert W. Kruger [and others] -- Asymmetric hydrogenation : a new route to pregabalin / Rex Jennings [and others] -- Responsibilities of the process chemist : beyond synthetic organic chemistry / Stéphane Caron -- Outsourcing : the challenge of science, speed, and quality / Simone Andler-Burzlaff, Jason Bertola, and Roger E. Marti -- Automation and the changing face of process research in the pharmaceutical industry / Edward J. Delaney [and others] -- Large scale synthesis : an engineering perspective / Joseph H. Childers, Jr. -- Synthesis and application of radioisotopes in pharmaceutical research and development / Larry E. Weaner and David C. Hoerr -- Selection of the drug form in exploratory development / George J. Quallich -- Strategies to control particle size of active pharmaceutical ingredients / David J. am Ende and Peter R. Rose -- Challenges in early formulation : turning drug substance into drug product / Mark H. Kleinman and Beeah Lee -- Intellectual property and early development / Maria I. Shchuka.
,
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
,
English.
Additional Edition:
Print version: Fundamentals of early clinical drug development. Hoboken, N.J. : Wiley-Interscience, ©2006 ISBN 0471692786
Language:
English
Subjects:
Chemistry/Pharmacy
Keywords:
Electronic books.
;
Electronic books.
;
Electronic books.
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/0470043407
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/0470043407
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/0470043407
