UID:
almafu_9959328724002883
Umfang:
1 online resource (xxiv, 463 pages) :
,
illustrations (some color), portrait
ISBN:
3527604022
,
9783527604029
,
3527603948
,
9783527603947
Serie:
Methods and principles in medicinal chemistry ; v. 22
Inhalt:
Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics. The first reference devoted to the topic, this up-to-date resource covers all stages of the early drug discovery process, from target selection to compound library and lead design. With the combined expertise of 20 research groups from academia and from leading pharmaceutical companies, this book is a must-have for every drug developer and medicinal chemist applying the powerful methods of chemogenomics to speed up the drug discovery process.
Anmerkung:
Target family-directed masterkeyes in chemogenomics /
,
Drug discovery from side effects /
,
The value of chemical genetics in drug discovery /
,
Structural aspects of binding site similarity: a 3D upgrade for chemogenomics /
,
The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds /
,
Chemical kinomics /
,
Structural aspects of kinases and their inhibitors /
,
A chemical genomics approach for ion channel modulators /
,
Phosphodiesterase inhibitors: a chemogenomic view /
,
Proteochemometrics: a tool for modeling the molecular interaction space /
,
Some principles related to chemogenomics in compound library and template design for GPCRs /
,
Computational filters in lead generation: targeting drug-like chemotypes /
,
Navigation in chemical space: ligand-based design of focused compound libraries /
,
Natural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates /
,
Combinatorial chemistry in the age of chemical genomics /
Weitere Ausg.:
Print version: Chemogenomics in drug discovery. Weinheim : Wiley-VCH, ©2004 ISBN 352730987X
Sprache:
Englisch
Schlagwort(e):
Electronic books.
;
Electronic books.
;
Electronic books.
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/3527603948
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/3527603948
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/3527603948
