UID:
almafu_9960073338802883
Format:
1 online resource (xvi, 359 pages) :
,
illustrations (some color)
ISBN:
9780124016972
,
0124016979
Series Statement:
Gale eBooks
Content:
Magnetic Resonance Spectroscopy covers how MRS is acquired, what it can measure, application to common research and clinical questions, and the advantages and limitations of the technique. Chapters are authored by experts in each topic area, and the book is written with a non-expert audience in mind. Magnetic resonance spectroscopy (MRS) is a noninvasive imaging technique that allows quantification of many neurochemicals. MRS is used in clinical neuroscience as a method for investigating brain neurochemistry, critical to understanding neurological and psychiatric disease. Imp
Note:
Description based upon print version of record.
,
Front Cover; Magnetic Resonance Spectroscopy; Copyright Page; Contents; Acknowledgements; Contributors; Introduction; Section 1: How MRS is Acquired; Section 2: Biochemistry-What Underlies the Signal?; Section 3: Applications of Proton MRS; Section 4: Applications of Non-Proton MRS; References; 1 Technical Aspects-How Mrs is Acquired; 1.1. Basis of Magnetic Resonance; Introduction; In Vivo Spectroscopy; MRS Methods; Basics of MRS; Chemical Shift; Scalar Coupling; Quantification of MR Spectra; Single-Voxel Spectroscopy; MR Spectroscopic Imaging; Water Suppression; Outer Volume Suppression
,
Magnetic Field Homogeneity and ShimmingChemical Shift Displacement; Sequence Imperfections and Eddy Currents; Advanced Techniques; Alternate Nuclei; Conclusions; References; 1.2. Localized Single-Voxel Magnetic Resonance Spectroscopy, Water Suppression, and Novel Approaches for Ultrashort Echo-Tim...; Introduction; Principles of Localization for Proton MRS; Challenges in Acquiring Quality Single-Voxel Proton MR Spectra; Instrumental Impacts on Volume Definition; RF Pulses; Slice-Selective 90° Pulses; Slice-Selective 180° Pulses for Inversion and Refocusing; Gradients
,
Chemical Shift DisplacementFactors Affecting Spectral Quality; Sensitivity; Magnetic Field Strength; RF Coil Performance; Field Homogeneity and Shimming; Water Suppression; Saturation with Frequency-Selective (Band-Selective) Pulse Excitation; Methods Based on T1 Relaxation Time; Frequency-Selective Refocusing; OVS; Benefits of Short Echo Time; Basic Localization 1H Mrs Methods; Localization Based on Slice-Selective Inversion; ISIS Localization; OVS Localization; Localization Based on Echo Formation; STEAM Localization; PRESS Localization
,
Localization by Adiabatic SElective Refocusing (LASER)Slice-Selective Localization by Adiabatic Selective Refocusing (Semi-LASER); Hybrid Sequence: SPin ECho Full Intensity Acquired Localized Localized (SPECIAL) Spectroscopy; Pros and Cons of Different Localization Schemes; Acknowledgments; References; 1.3. Technical Considerations for Multivoxel Approaches and Magnetic Resonance Spectroscopic Imaging; Introduction; Multivolume Selection; Spatial Encoding; RF Encoding; Gradient-Based Encoding; Fast Gradient-Encoding Methods; Encoding Based on Prior Knowledge; Water Suppression
,
Lipid SuppressionB0 Shimming; Conclusions; References; 1.4. Spectral Editing and 2D NMR; Introduction; Scalar Coupling; Scalar Coupling Evolution; In Vivo GABA Editing; 2D NMR Spectroscopy; References; 1.5. Spectral Quantification and Pitfalls in Interpreting Magnetic Resonance Spectroscopic Data: What To Look Out For; Introduction: A Simple Example of Spectral Quantitation; Measuring Peak Intensity; Peak Integration; Peak Fitting; Basis Spectrum Fitting; Nuisance Signals; Macromolecules; Lipids; Unsuppressed Water; Spectral Baseline; Software Packages for Spectral Quantification; AQSES
,
jMRUI
,
English
Additional Edition:
ISBN 9780124016880
Additional Edition:
ISBN 012401688X
Additional Edition:
ISBN 9781306133173
Additional Edition:
ISBN 1306133173
Language:
English
