UID:
almafu_9960073770402883
Umfang:
1 online resource (497 p.)
Ausgabe:
1st ed.
ISBN:
1-283-35495-0
,
9786613354952
,
0-12-391449-3
Serie:
Elsevier insights
Inhalt:
The relatively new technique of solid phase microextraction (SPME) is an important tool to prepare samples both in the lab and on-site. SPME is a ""green"" technology because it eliminates organic solvents from analytical laboratory and can be used in environmental, food and fragrance, and forensic and drug analysis. This handbook offers a thorough background of the theory and practical implementation of SPME. SPME protocols are presented outlining each stage of the method and providing useful tips and potential pitfalls. In addition, devices and fiber coatings, automated SPME systems, SPME
Anmerkung:
Description based upon print version of record.
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Front Cover; Handbook of Solid Phase Microextraction; Copyright Page; Contents; Preface; List of Contributors; 1 Solid-Phase Microextraction in Perspective; 1.1 Sample Preparation as Part of the Analytical Process; 1.2 Classification of Extraction Techniques; 1.3 Perspective on Microextraction Techniques; 1.4 Implementations of SPME; 1.5 Miniaturisation and Integration; 1.6 In Vivo Analysis; 1.7 SPME Versus SPE; References; 2 Theory of Solid-Phase Microextraction; 2.1 Introduction; 2.2 SPME Principle; 2.3 Thermodynamics; 2.3.1 Distribution Constant; 2.3.2 Estimation of Distribution Constants
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2.3.3 Effect of Extraction Parameters on Distribution Constants2.3.3.1 Temperature; 2.3.3.2 Salting; 2.3.3.3 pH; 2.3.3.4 Polarity of Sample Matrix and Coating Material; 2.3.4 Distribution Constants in the Heating-Cooling Environment; 2.3.5 Multiphase Equilibria in SPME; 2.3.6 Matrix Effects; 2.3.7 Characteristics of the Extraction Phases; 2.4 Kinetics; 2.4.1 Direct Extraction; 2.4.1.1 Perfect Agitation; 2.4.1.2 Practical Agitation; 2.4.2 Desorption of Extracted Analytes; 2.4.3 Headspace Extraction; 2.4.4 Indirect SPME Extraction Through a Membrane; 2.5 Extraction with Derivatisation
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2.6 Extraction of Sample Matrices Containing Solids2.6.1 Convolution Model of Extraction; 2.7 Solid Versus Liquid Sorbents; 2.8 Passive TWA Sampling; 2.9 In-Tube SPME; 2.10 Experimental Verification; References; 3 Development of SPME Devices and Coatings; 3.1 Historical Perspective; 3.2 Rational Design of SPME Devices; 3.2.1 Agitation for Air Sampling; 3.2.2 Agitation for Aqueous Sampling; 3.2.3 Cold-Fibre SPME; 3.2.4 High-Surface-Area Samplers (Thin-Film Microextraction); 3.3 On-Site Samplers; 3.3.1 Field Samplers; 3.3.2 NT Devices; 3.3.3 TWA Devices; 3.3.4 In Vivo Samplers
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3.4 Development of New SPME Coatings3.4.1 Coating Preparation Methods; 3.4.1.1 Dipping Technique; 3.4.1.2 Electrodeposition; 3.4.1.3 Hollow Fibre Membranes/Adhesive Tape; 3.4.1.4 Adhesion of Coatings; 3.4.1.5 Conducting Polymers; 3.4.1.6 Sol-Gel Coatings; 3.4.2 Affinity-Based Coatings; 3.4.2.1 Molecularly Imprinted Polymer Coatings; 3.4.2.2 Immunoaffinity Coatings; 3.4.3 Biocompatible Coatings; 3.4.3.1 Biocompatible Polymer Coatings; 3.4.3.2 Restricted Access Materials; 3.5 Interfaces to Analytical Instrumentation; 3.5.1 SPME-GC Interface; 3.5.2 Field Portable SPME-Fast GC
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3.5.3 SPME-HPLC Interface3.5.4 SPME-MALDI Interface; 3.5.5 SPME-Nanospray MS Interface; 3.5.6 Other Interfaces; References; 4 SPME Commercial Devices and Fibre Coatings; 4.1 Introduction; 4.2 Description of SPME Fibre Assemblies and Holders; 4.2.1 Assemblies with 24- Versus 23-Gauge Needles; 4.2.2 GC Inlet Seals; 4.3 Description of Fibre Cores, Coatings and the Coating Process; 4.3.1 Types and Selection of Fibre Cores; 4.3.1.1 Fused Silica Core; 4.3.1.2 Stableflex Fibre Core; 4.3.1.3 Metal Fibre Core; 4.3.2 Types of Commercially Available SPME Coatings; 4.3.2.1 Determination of Phase Volume
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4.3.2.2 Fibre Coating Temperature and pH Ranges
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English
Weitere Ausg.:
ISBN 0-12-416017-4
Sprache:
Englisch
