UID:
almafu_9961427387502883
Umfang:
1 videorecording (34 min., 32 sec.)
,
003432
Inhalt:
Audio-visual presentation: Simple contingency table tests: genotypic test and Cochran-Armitage trend test -- Logistic regression model for binary (case-control) data: incorporating covariates and extension to allow for multi-locus effects and interactions -- Quantitative trait association analysis -- Haplotype analysis: allowing for phase uncertainty in logistic regression model and methods for haplotype clustering -- Software: statistical tests of association, genome-wide association analysis and haplotype analysis.
Anmerkung:
Retrieved April 9, 2024, from https://hstalks.com/bs/869/.
,
Introduction -- Introduction to statistical tests for association -- Lecture outline -- Single-locus tests of association (1) -- Single-locus tests of association (2) -- Single-locus Cochran-Armitage trend tests -- Interpretation of test results -- Logistic regression model -- Trend test of association -- Genotypic test of association -- General disease models -- Allowing for covariates -- Example -- Quantitative traits -- Multi-locus models -- Multi-locus trend model of association -- Software for whole genome association analysis -- Haplotype association with disease -- Modelling haplotype effects -- Unknown phase -- Allowing for unknown phase -- Parsimony issues -- Haplotype evolution -- Haplotype clustering -- Software for haplotype analysis -- When is haplotype analysis appropriate? -- References.
Sprache:
Englisch
