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  • 1
    UID:
    almafu_9961574124502883
    Format: 1 online resource (1098 pages)
    Edition: 2nd ed. 2024.
    ISBN: 9783031440878
    Series Statement: Advances in Experimental Medicine and Biology, 1441
    Content: This 2nd edition has been extensively updated and provides comprehensive and current insight into congenital heart diseases, from embryonic development through to clinical features, including human genetics and our current knowledge of the underlying molecular pathways. The book is divided into three parts: an introduction to the development of the heart and its vessels, an overview of the molecular pathways affecting the development of various cardiovascular structures, and a main section focusing on the different types of structural and nonstructural congenital heart diseases, including their clinical features, underlying genetic alterations and insights from animal models and pathways. All chapters have been updated and new chapters added on state-of-the-art approaches including stem cells and organoids, cardiac metabolism, single cell transcriptomics and 3D reconstruction of human heart development. The clinical chapters have been extended and include new sections on diagnostic imaging techniques. Taken together, the book, written by and for clinicians and researchers, provides an integrated and up-to-date resource for all those who want to learn more about both the clinical aspects and the genetic and molecular basis of congenital heart disease.
    Note: Section I: General introduction in cardiac development -- Section II: Different chapters covering the different types of congenital heart disease -- Section III: The overall perspective.
    Additional Edition: Print version: Rickert-Sperling, Silke Congenital Heart Diseases: the Broken Heart Cham : Springer International Publishing AG,c2024 ISBN 9783031440861
    Language: English
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