UID:
almahu_9947358103802882
Umfang:
1 online resource (285 p.)
Ausgabe:
1st ed.
ISBN:
1-84973-301-5
Serie:
RSC drug discovery series, no. 7
Inhalt:
Since Alois Alzheimer described the results of his postmortem studies in 1906, significant strides have been made in understanding the pathogenesis of neurodegenerative diseases. Substantial evidence has accumulated indicating that diverse neurodegenerative disorders might share a common pathological mechanism: the misfolding, aggregation and accumulation of proteins (termed ""amyloid"") in the brain. Metal ions have long been thought to catalyze protein misfolding initiating a cascade of events resulting in oxidative damage and neurodegeneration. They have, consequently, been seen as a suitab
Anmerkung:
Description based upon print version of record.
,
i-iv; v-viii; xi-xiv; 1-17.PDF.pdf; 18-45; 46-68; 69-82; 83-111; 112-140; 141-151; 152-173; 174-211; 212-225; 226-248; 249-258; 259-270
,
English
Weitere Ausg.:
ISBN 1-84973-050-4
Sprache:
Englisch
