UID:
almafu_9960119213602883
Umfang:
1 online resource (xii, 323 pages) :
,
digital, PDF file(s).
Ausgabe:
1st ed.
ISBN:
1-139-16496-1
Serie:
Cambridge studies in philosophy and biology
Inhalt:
Between 1940 and 1970 pioneers in the new field of cell biology discovered the operative parts of cells and their contributions to cell life. They offered mechanistic accounts that explained cellular phenomena by identifying the relevant parts of cells, the biochemical operations they performed, and the way in which these parts and operations were organised to accomplish important functions. Cell biology was a revolutionary science but in this book it also provides fuel for yet another revolution, one that focuses on the very conception of science itself. Laws have traditionally been regarded as the primary vehicle of explanation, but in the emerging philosophy of science it is mechanisms that do the explanatory work. Bechtel emphasises how mechanisms were discovered, focusing especially on the way in which new instruments made these inquiries possible. He also describes how new journals and societies provided institutional structure to this new enterprise.
Anmerkung:
Title from publisher's bibliographic system (viewed on 05 Oct 2015).
,
Cover -- Half-title -- Cambridge Studies in Philosophy and Biology -- Title -- Copyright -- Contents -- Preface -- Introduction: Cell Mechanisms and Cell Biology -- 1. A Different Kind of Science -- 2. The Organization of Science into Disciplines -- 3. The New Discipline of Cell Biology -- Explaining Cellular Phenomena through Mechanisms -- 1. Historical Conceptions of Mechanism -- 2. Twentieth-Century Conceptions of Mechanism -- 3. Current Conceptions of Mechanism -- 4. Representing and Reasoning about Mechanisms -- 5. Levels of Organization and Reduction -- 6. Organization: From Cartesian to Biological Mechanisms -- 7. Discovering and Testing Models of Mechanisms -- 8. Conclusion -- The Locus of Cell Mechanisms: Terra Incognita between Cytology and Biochemistry -- 1. Cytological Contributions to Discovering Cell Mechanisms up to 1940 -- 2. Biochemical Contributions to Discovering Cell Mechanisms up to 1940 -- 3. The Need to Enter the Terra Incognita between Cytology and Biochemistry -- Creating New Instruments and Research Techniques for Discovering Cell Mechanisms -- 1. The Epistemology of Evidence: Judging Artifacts -- 2. The Ultracentrifuge and Cell Fractionation -- 3. The Electron Microscope and Electron Microsopy -- 4. A Case Study of an Artifact Charge -- 5. Equipped with New Instruments and Techniques to Enter Terra Incognita -- Entering the Terra Incognita between Biochemistry and Cytology: Putting New Research Tools to Work in the 1940s -- 1. First Steps toward Cell Biology at the Rockefeller Institute: Claude's Introduction of Cell Fractionation -- 2. Robert Bensley: An Alternative Approach to Fractionation -- 3. Competing Interpretations of Fractions from Normal Cells -- 4. Linking Claude's Microsomes to Protein Synthesis -- 5. Adding a Biochemical Perspective to the Rockefeller Laboratory -- 6. Adding Electron Microscopy as a Tool.
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7. The State of Cell Studies at the End of the 1940s -- New Knowledge: The Mechanisms of the Cytoplasm -- 1. The Mitochondrion -- 2. Microsomes, the Endoplasmic Reticulum, and Ribosomes -- 3. Two Additional Organelles -- 4. Conclusion -- Giving Cell Biology an Institutional Identity -- 1. Creation of the Journal of Biophysical and Biochemical Cytology -- 2. Creation of the American Society for Cell Biology -- 3. Conclusion -- Afterword -- References -- Index.
,
English
Weitere Ausg.:
ISBN 0-521-72944-0
Weitere Ausg.:
ISBN 0-521-81247-X
Sprache:
Englisch
Fachgebiete:
Biologie
URL:
Volltext
(URL des Erstveröffentlichers)
URL:
Volltext
(lizenzpflichtig)
URL:
https://doi.org/10.1017/CBO9781139164962
