UID:
almahu_9948025404202882
Format:
1 online resource (600 p.)
Edition:
3rd ed.
ISBN:
1-78402-032-X
,
1-282-95392-3
,
9786612953927
,
0-08-091865-4
Content:
Significant advances in our knowledge of genetics were made during the twentieth century but in the most recent decades, genetic research has dramatically increased its impact throughout society. Genetic issues are now playing a large role in health and public policy, and new knowledge in this field will continue to have significant implications for individuals and society. Written for the non-majors human genetics course, Human Genetics, 3E will increase the genetics knowledge of students who are learning about human genetics for the first time. This thorough revision of the best-selling Hum
Note:
First ed. by R. Scott Hawley and Catherine A. Mori.
,
Front Cover; The Human Genome; Copyright Page; Contents; Acknowledgments; Prologue: The Answer in a Nutshell; SECTION I: HOW GENES SPECIFY A TRAIT; Chapter 1 The Basics of Heredity: How Traits Are Passed Along in Families; 1.1 Mendel's Laws; 1.2 Selection: Artificial, Natural, and Sexual; 1.3 Human Genetic Diversity; 1.4 Human Dominant Inheritance; 1.5 Human Recessive Inheritance; 1.6 Complementation; 1.7 Epistasis and Pleiotropy; 1.8 Complex Syndromes; 1.9 One Man's Disease Is Another Man's Trait; Chapter 2 The Double Helix: How Cells Preserve Genetic Information; 2.1 Inside the Cell
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2.2 DNA: The Repository of Genetic Information2.3 DNA and the Double Helix; 2.4 DNA Replication; 2.5 Chromatin; 2.6 What Are Chromosomes?; 2.7 Euchromatin and Heterochromatin; 2.8 The Mitochondrial Chromosome: The ""Other Genome"" in the Human Genome; 2.9 DNA in vitro; SECTION II: HOW GENES FUNCTION; Chapter 3 The Central Dogma of Molecular Biology: How Cells Orchestrate the Use of Genetic Information; 3.1 What Is RNA?; 3.2 What Is RNA For?; 3.3 Transcription of RNA; 3.4 Orchestrating Expression; 3.5 Monitoring Gene Expression; 3.6 Interaction of Transcription Factors; 3.7 Inducible Genes
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3.8 Epigenetic Control of Gene Expression3.9 What Constitutes Normal?; Chapter 4 The Genetic Code: How the Cell Makes Proteins from Genetic Information Encoded in mRNA Molecules; 4.1 The Genetic Code; 4.2 Moving Things In and Out of the Nucleus; 4.3 The Central Dogma of Molecular Biology; 4.4 Translation; 4.5 Messenger RNA Structure; 4.6 Splicing; 4.7 Modular Genes; 4.8 What Are Proteins?; 4.9 Gene Products and Development; Chapter 5 We Are All Mutants: How Mutation Alters Function; 5.1 What Is a Mutation?; 5.2 The Process of Mutation; 5.3 How We Detect Mutations; 5.4 Basic Mutations
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5.5 Mutations in DNA Sequences that Regulate Gene Expression5.6 Copy Number Variation: Too Much or Too Little of a Good Thing; 5.7 Expanded Repeat Traits; 5.8 The Male Biological Clock; 5.9 Mutation Target Size; 5.10 Absent Essentials and Monkey Wrenches; SECTION III: HOW CHROMOSOMES MOVE; Chapter 6 Mitosis and Meiosis: How Cells Move Your Genes Around; 6.1 The Cell Cycle; 6.2 Mitosis; 6.3 Gametogenesis: What Is Meiosis Trying to Accomplish?; 6.4 Meiosis in Detail; 6.5 Mechanisms of Chromosome Pairing in Meiosis; 6.6 The Chromosomal Basis of Heredity
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6.7 Aneuploidy: When Too Much or Too Little Counts6.8 Uniparental Disomy; 6.9 Partial Aneuploidies; 6.10 The Female Biological Clock; Appendix 6.1 Failed Meiotic Segregation (Nondisjunction) as Proof of the Chromosome Theory of Heredity; Chapter 7 The Odd Couple: How the X and Y Chromosomes Break the Rules; 7.1 Passing the X and Y Chromosomes between Generations; 7.2 How Humans Cope with the Difference in Number of Sex Chromosomes between Males and Females; 7.3 How X Inactivation Works; 7.4 Skewed X Inactivation - When Most Cells Inactivate the Same X; 7.5 Genes that Escape X-Inactivation
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7.6 Reactivation of the Inactive X Chromosome in the Female Germline
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English
Additional Edition:
ISBN 0-12-333445-4
Language:
English
