UID:
almahu_9948025695302882
Umfang:
1 online resource (243 p.)
ISBN:
1-281-04623-X
,
9786611046231
,
0-08-052682-9
Serie:
Advances in veterinary medicine ; v. 40
Inhalt:
Animal science is being transformed by advances in molecular genetics. This book covers this exciting transformation. Both the diagnosis and treatment of disease are discussed in seven chapters by a team of leading international authorities. From oncogenesis and hemophilia to retroviral virulence and genome mapping, this volume yields an understanding of fundamental mechanisms of action and insightful means of diagnosis and treatment. Practicing veterinarians and researchers in animal science will find this book useful.
Anmerkung:
Description based upon print version of record.
,
Front Cover; Molecular Genetics, Gene Transfer, and Therapy; Copyright Page; Contents; Contributors; Preface; Chapter I. From Molecular Genetics to Diagnosis and Gene Therapy; I. Introduction to Molecular Genetics; II. Gene Manipulation; III. Studies of Metabolic and Gene Regulation; IV. Diagnosis of Genetic Disease; V. Therapy of Genetic Diseases; VI. Use of Recombinant DNA Methods to Improve Domestic Animals; VII. Legal and Ethical Aspects of Patenting Biotechnology; References; Chapter II. Genes Involved in Oncogenesis; I. Introduction; II. Detection of Genes Involved in Oncogenesis
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III. Mapping and Cloning Genes Involved in OncogenesisIV. Animal Model Systems Used to Study Gene Function; V. Identity and Function of Genes Involved in Oncogenesis; VI. Applications of Oncogene Research; VII. Conclusion; References; Chapter III. Diagnostic Molecular Genetics; I. Introduction; II. Methods; III. Linkage Analysis; IV. Single-Gene Disorders; V. Future Directions; Acknowledgments; References; Chapter IV. Gene Therapy for the Hemophilias; I. Introduction; II. Advantages of Gene Therapy as a Treatment for Hemophilia; III. Advantages of Hemophilia as a Model for Gene Therapy
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IV. Choice of VectorV. Factor IX; VI. Factor VIII; VII. Summary; References; Chapter V. Genes Controlling Retroviral Virulence; I. Introduction; II. Retrovirus Structure and Replication; III. Additional Retrovirus Genes; IV. Feline Acquired Immunodeficiency Syndrome; V. Murine AIDS; VI. Simian AIDS; VII. Murine Leukemia Virus; VIII. Endogenous Retroviruses; IX. Lentiviruses; References; Chapter VI. Mapping Animal Genomes; I. Introduction; II. Why Map Farm Animal Genomes; III. Methods for Animal Genome Mapping; IV. Current Status of Animal Genome Maps; V. Future Directions; References
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Chapter VII. The Canine GenomeI. Introduction; II. Applications of a Canine Genetic Map; III. Organization of the Canine Genome; IV. Development of a Canine Genetic Map; V. Targeted Cloning of Canine Genes; VI. Considerations and Conclusions; References; Index
,
English
Weitere Ausg.:
ISBN 0-12-039241-0
Sprache:
Englisch
