UID:
almahu_9948025874102882
Format:
1 online resource (212 pages)
ISBN:
1-281-01944-5
,
9786611019440
,
0-08-052677-2
Series Statement:
Advances in medicinal chemistry ; 5
Content:
Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors.
Note:
Cover; Copyright Page; CONTENTS; LIST OF CONTRIBUTORS; PREFACE; CHAPTER 1. IMMUNOPHILINS: THE NEXT GENERATION; CHAPTER 2. DISCOVERY OF ABT-594 AND RELATED NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS AS ANALGESIC AGENTS: MEDICINAL CHEMISTRY AND BIOLOGY; CHAPTER 3. DISCOVERY AND PRECLINICAL EVALUATION OF NOVEL DOPAMINE PARTIAL AGONISTS AS ANTIPSYCHOTIC AGENTS; CHAPTER 4. NONPEPTIDE INHIBITORS OF HIV PROTEASE; INDEX
,
English
Additional Edition:
ISBN 0-7623-0593-2
Language:
English