UID:
almahu_9948025923702882
Umfang:
1 online resource (507 p.)
ISBN:
0-08-093321-1
,
1-299-19286-6
Serie:
Comprehensive biochemistry. Section 6, volume 38, A history of biochemistry. Selected topics in the history of biochemistry. Personal recollections ; 4
Inhalt:
The editors invited selected authors who had participated in or observed developments in biochemistry and molecular biology, particularly in the second half of this century, to record their personal recollections of the times and circumstances in which they worked. Having been given free reign, both content and style of the contruibutions reflect the flavour of the personality of the author. The book reflects the explosive development of biochemistry and molecular biology and related sciences that had led to the almost unique situation of these fields coming of age at a time when their found
Anmerkung:
Description based upon print version of record.
,
Front Cover; Selected Topics in the History of Biochemistry Personal Recollections, IV; Copyright Page; Preface to Volume 38; Contributors to this Volume; In Memoriam; Table of Contents; Chapter 1. Life, Luck and Logic in Biochemical Research; Chapter 2. Memories of Heidelberg - and of Other Places; Early life in Munich; The first years in Heidelberg; Research and teaching; Lactic acid dehydrogenases; The time in Mainz; Biochemical research after the war; First journey to the USA; Johann Wolfgang Goethe University in Frankfurt a. Ì; Half a century of mushroom research
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An import system in liver cellsStructures of the phytotoxins; Oxidative phosphorylation; Enzymatic peptide synthesis; The plastein reaction; Again in Heidelberg; Retrospection; Acknowledgements; Appendix; References; Chapter 3. Stepping Stones - Building Bridges; Between two wars; The painful transition from the fragile Weimar Republic to the tyranny of the Third Reich; Chemistry in Munich: Richard Willstätter and Heinrich Wieland; 'Kristallnacht' or the 'Night of Broken Glass'; Dissertation on the toxin of the deathcap; The end of the war; Harvard University, 1947-1950
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Colleagues and friendsAmino acids - then and now; Much 'trypto-fun' and the International Study Group for Tryptophan Research (ISTRY); Albert Hofmann's 'Problem Child'; Probing sequences of the gramicidins, serum albumins and TMV virus; Origin and fate of norepinephrine in man and in insects; Labile metabolites; Cyanogen bromide: from protein sequencing to protein accounting; Photoreduction of uridine and thymidine; Wieland's legacy: from toads to frogs to birds; Epilogue; References; Chapter 4. Recollections: Vacillation of a Classical Biochemist; The early years in Munich
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St. Louis, 1954-1968Würzburg, 1968-1991; Retirement and new challenges; References; Chapter 5. These are the Moments when we Live! From Thunberg Tubes and Manometry to Phone, Fax and Fedex; Comments on being an experimental scientist; The moments when; Water, copper and yeast amylase; Adventures in fatty acid oxidation; The quest for CoA; Flavoproteins of fatty acid β-oxidation; Intermediates in fatty acid dehydrogenation; semiquinones?; Additional dehydrogenases and 3D structure; First ventures with EPR; Copper in cytochrome c oxidase; High spin heme in cytochrome c oxidase
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Non-heme iron: iron-sulfur proteinsIron-sulfur proteins of the mitochondrial respiratory chain; Iron-sulfur clusters in non-oxidative enzymes; aconitase; The Janus-faced protein; Reminder: Some moments when not; Dedication; Addendum; References; Chapter 6. Chorismic Acid and Beyond; Scientific beginnings; First steps in research; Aromatic biosynthesis; A change of direction; Menaquinone and ubiquinone: biosynthesis and function; Phenolic compounds and iron transport; ATPase and oxidative phosphorylation; A trail of research; Miscellanea; Acknowledgements; References
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Chapter 7. Charge Separation: A Personal Involvement in a Fundamental Biological Process
Weitere Ausg.:
ISBN 0-444-81942-8
Sprache:
Englisch
