UID:
almahu_9948025997302882
Umfang:
1 online resource (385 p.)
ISBN:
1-299-36540-X
,
0-323-15293-7
Inhalt:
Strategies and Tactics In Organic Synthesis
Anmerkung:
Description based upon print version of record.
,
Front Cover; Strategies and Tactics in Organic Synthesis; Copyright Page; Table of Contents; CONTRIBUTORS; PREFACE; CHAPTER 1. THEME AND VARIATIONS: A SYNTHESIS OF SUPERPHANE; I. Introduction, Goals, and Synthetic Philosophy; II. Theme; III. Variations; IV. A Synthesis of Superphane; V. Further Variations; References; CHAPTER 2. THE TOTAL SYNTHESIS OF GIBBERELLIC ACID; I. Introduction; II. The Synthetic Challenge; III. The Synthetic Strategy; IV. Preliminary Studies: Stereocontrolled Elaboration of the A Ring; V. Model Studies: The Intramolecular Diels-Alder Strategy Is Tested
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VI. Model Studies: A Method for the Construction of the C and D RingsVII. The Hydrindane Approach; VIII. The Hydronaphthalene Approach: (1) The Advance to Chandra's Dione; IX. The Hydronaphthalene Approach: (2) Operations on the C Ring; X. The Hydronaphthalene Approach: (3) The D Ring; XI. The Hydronaphthalene Approach: (4) Subjugation of the B Ring; XII. The Hydronaphthalene Approach: (5) The Triumph of the Intramolecular Diels-Alder Strategy; XIII. The Hydronaphthalene Approach: (6) Stalemate at the A Ring; XIV. The Total Synthesis of Gibberellic Acid; References
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CHAPTER 3. A PROSTAGLANDIN SYNTHESISI. Introduction; II. 7-Oxaprostaglandins; III. Prostaglandin F 2x; IV. 13,14-Dehydroprostaglandins; References; CHAPTER 4. SYNTHESIS OF INDOLE ALKALOIDS; I. Introduction; II. Early Thoughts; III. Initial Results: First Phase; IV. Flexible Strategy-Flexible Tactics: Second Phase; V. Synthesis of (±)-Aspidospermidine: Third Phase; VI. Reverse Roles: Fourth Phase; VII. Completion of the ""Model Work""; VIII. New Territory; References; CHAPTER 5. SYNTHESIS OF TYLONOLIDE, THE AGLYCONE OF TYLOSIN; I. Introduction; II. General Strategy; III. Preliminary Work
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IV. SynthesisV. Concluding Remarks; References; CHAPTER 6. PERICYCLIC REACTIONS IN ORGANIC SYNTHESIS AND BIOSYNTHESIS: SYNTHETIC ADVENTURES WITH ENDIANDRIC ACIDS A - G; I. Introduction: The Appealing Endiandric Acid Cascade; II. Retrosynthetic Analysis of Endiandric Acids A-G; III. Synthesis of the Key Bicyclic Intermediate; IV. Functionalization of the Bicyclic Intermediate: Synthesis of Endiandric Acids D, E, F, and G; V. The Intramolecular Diels-Alder Reactions: Synthesis of Endiandric Acids A, B, and C; VI. Conclusions; References
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CHAPTER 7. PLATO'S SOLID IN A RETORT: THE DODECAHEDRANE STORYI. Introduction; II. The Decision against Convergency and Building of the Cornerstone; III. A Retrosynthetic Glimpse and Symmetry Considerations; IV. Arrival at the ""Closed"" and ""Open"" Dilactones; V. Chemical Reactivity of the ""Open"" Dilactone; VI. Functionalization Reactions of the ""Closed"" Dilactone; VII. (C2)-Dioxa-C2o-octaquinane, a Heterocyclic Trisecododecahedrane; VIII. The Pilot Photochemical Experiment; IX. Trisecododecahedranes via Dichloro Diester Reduction; X. The Monoseco Level of Elaboration
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XI. Installation of the Final Bond: Formation of 1,16-Dimethyldodecahedrane
Weitere Ausg.:
ISBN 0-12-450280-6
Sprache:
Englisch
