UID:
almahu_9948026355602882
Format:
1 online resource (338 pages) :
,
illustrations
ISBN:
1-281-30868-4
,
9786611308681
,
0-08-052637-3
Series Statement:
Advances in medicinal chemistry,
Content:
Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important antica
Note:
Front Cover; Advances in Medicinal Chemistry; Copyright Page; CONTENTS; LIST OF CONTRIBUTORS; PREFACE; CHAPTER 1. NOVEL PEPTIDE MIMETIC BUILDING BLOCKS AND STRATEGIES FOR EFFICIENT LEAD FINDING; CHAPTER 2. RECENT ADVANCES IN THE MEDICINAL CHEMISTRY OF TAXOID ANTICANCER AGENTS; CHAPTER 3. SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIPS OF PEROXIDIC ANTIMALARIALS BASED ON ARTEMISININ; CHAPTER 4. DESIGN OF COMPOUND LIBRARIES FOR DETECTING AND PURSUING NOVEL SMALL MOLECULE LEADS
,
CHAPTER 5. A THEORETICAL MODEL OF THE HUMAN THROMBIN RECEPTOR (PAR-1), THE FIRST KNOWN PROTEASE-ACTIVATED G-PROTEIN-COUPLED RECEPTORCHAPTER 6. FARNESYL TRANSFERASE INHIBITORS: DESIGN OF A NEW CLASS OF CANCER CHEMOTHERAPEUTIC AGENTS; INDEX
,
English
Additional Edition:
ISBN 0-7623-0064-7
Language:
English
