UID:
almahu_9948026717802882
Format:
1 online resource (342 p.)
Edition:
1st ed.
ISBN:
1-280-63095-7
,
9786610630950
,
0-08-045611-1
Series Statement:
Studies in interface science, v. 21
Content:
Surface activity is present in living systems; for example in body fluid or cell soup and molecules of surface-active nature are crucial to living matter and its organization. Surface Activity in Drug Action proposes ""a liquid membrane hypothesis of drug action"" for surface-active drugs. Chapters 1-7 contains an account of the hypothesis and chapter 8 contains a general account of the application of surface activity in therapeutics. The methodology and presentation of the information makes Surface Activity in Drug Action valuable reading for students and researchers interested
Note:
Description based upon print version of record.
,
Front Cover; Surface Activity in Drug Action; Copyright Page; Preface; Table of Contents; Chapter 1. Introduction and scope; Introduction; References; Chapter 2. Surface activity of drugs; 2.1 Analgesics; 2.2. Antimicorbials; 2.3. Drugs acting on autonomic nervous system; 2.4. Antihistarmnes; 2.5. Drugs affecting renal and cardiovascular function; 2.6. Drugs acting on central nervous system; 2.7 Miscellaneous; Reference; Chapter 3. Theories of drug action; 3.1 Commonly used terms; 3.2 Theories of drug action; 3.3 Occupancy theory; References
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Chapter 4. The liquid membrane hypothesis of drug action4.1 The liquid membrane hypothesis; 4.2 The liquid membrane hypothesis of drug action; References; Chapter 5. Liquid membranes as biomimetic system; 5.1 Introduction; 5.2 Liquid membranes from cholesterol, lecithin and lecithin-cholesterol mixtures; 5.3 Mimicking light-induced transport; 5.4 Hydrophilic Pathways; 5.5 Mimicking electrical excitability of liquid membrane bilayers; References; Chapter 6. Role of liquid membranes in drug action - experimental studies; 6.1 The design of experiments; 6.2 Experimental studies; References
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Chapter 7. Assessment of the Hypothesis7.1 Implications of the hypothesis; 7.2 The liquid membrane hypothesis vis-a-vis existingtheories of drug actions; References; Chapter 8. Application of surface activity in therapeutics; 8.1 Drug Absorption; 8.2 Solublizing agents; 8.3 Dissolution; 8.4 Drug stabilization; 8.5 Surfactants in drug targeting; 8.6 Surfactants as wetting agents; 8.7 Synergistic effects; 8.8 Prodrugs; 8.9 Surfactants and drug delivery; 8.10 Miscellaneous; References; Epilogue; Authors index; Subject index
,
English
Additional Edition:
ISBN 0-444-51715-4
Language:
English
