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  • 1
    UID:
    almahu_9948198288002882
    Format: 1 online resource (xxii, 414 pages) : , illustrations (some color)
    ISBN: 9783527676132 , 3527676139 , 9783527676149 , 3527676147 , 9783527676156 , 3527676155 , 9783527676163 , 3527676163
    Content: By integrating knowledge from pharmacology, microbiology, molecular medicine, and engineering, researchers from Europe, the U.S. and Asia cover a broad spectrum of current and potential antimicrobial medications and treatments. The result is a comprehensive survey ranging from small-molecule antibiotics to antimicrobial peptides and their engineered mimetics, from enzymes to nucleic acid therapeutics, from metallic nanoparticles to photo- and sonosensitizers and to phage therapy. In each case, the therapeutic approaches are compared in terms of their mechanisms, likelihood to induce resistance.
    Note: The problem of microbial drug resistance -- Conventional antibiotics -- revitalized by new agents -- Developing novel bacterial targets: carbonic anhydrases as antibacterial drug targets -- Magainins -- a model for development of eukaryotic antimicrobial peptides (amps) -- Antimicrobial peptides from prokaryotes -- Peptidomimetics as antimicrobial agents -- Synthetic biology and therapies for infectious diseases -- Nano-antimicrobials based on metals -- Natural products as antimicrobial agents -- an update -- Photodynamic antimicrobial chemotherapy -- The antimicrobial effects of ultrasound -- Antimicrobial therapy based on antisense agents -- New delivery systems -- liposomes for pulmonary delivery of antibacterial drugs.
    Additional Edition: Print version: Novel antimicrobial agents and strategies. Weinheim : Wiley-VCH Verlag GmbH & Co. KGaA, [2015] ISBN 9783527336388
    Language: English
    Keywords: Electronic books.
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