UID:
almahu_9948234030202882
Format:
1 online resource (xvi, 960 pages) :
,
digital, PDF file(s).
Edition:
Second edition.
ISBN:
9780511471001 (ebook)
Content:
Childhood leukemias represent nearly one third of all cancers in children and present a unique challenge to oncologists, pediatricians, hematologists, and other health professionals. Dr Ching-Hon Pui has assembled an expert team of authors to develop the most comprehensive, clinically-oriented, and authoritative reference dedicated to these diseases. Childhood Leukemias moves from the laboratory bench to the patient bedside in four easily-accessible sections. Part one presents an historical overview, whilst part two presents an in-depth review of topics needed to understand the pathobiology of leukemia. Part three builds upon this scientific foundation by explaining practical approaches to clinical diagnosis, evaluation, and treatment, and part four outlines major clinical complications which may arise during and after treatment, along with chapters on supportive care, psychosocial issues, and nursing. Fully referenced and up-to-date, Childhood Leukemias is an absolute 'must-have' for any physician or investigator who deals with leukemias in childhood.
Note:
Title from publisher's bibliographic system (viewed on 05 Oct 2015).
,
History and general issues. Historical perspective / Donald Pinkel. Diagnosis and classification / Mihaela Onciu and Ching-Hon Pui. Epidemiology and etiology / Logan G. Spector ... [et al.] -- Cell biology and pathobiology. Anatomy and physiology of hematopoiesis / Connie J. Eaves and Allen C. Eaves. Hematopoietic growth factors / James N. Ihle. Signal transduction in the regulation of hematopoiesis / James N. Ihle. Immunophenotyping / Fred G. Behm. Immunoglobulin and T-cell receptor gene rearrangements / Jacques J.M. van Dongen and Anton W. Langerak. Cytogenetics of acute leukemias / Susana C. Raimondi. Molecular genetics of acute lymphoblastic leukemia / Adolfo A. Ferrando, Jeffrey E. Rubnitz, and A. Thomas Look. Molecular genetics of acute myeloid leukemia / Robert B. Lorsbach and James R. Downing. Apoptosis and chemoresistance / Kirsteen H. Maclean and John L. Cleveland. Heritable predispositions to childhood hematologic malignancies / Doan Le, Kevin Shannon, and Beverly J. Lange -- Evaluation and treatment. Pharmacokinetic, pharmacodynamic, and pharmacogenetic considerations / Shinji Kishi, William E. Evans, and Mary V. Relling. Assays and molecular determinants of cellular drug resistance / Monique L. den Boer and Rob Pieters. Acute lymphoblastic leukemia / Ching-Hon Pui. Relapsed acute lymphoblastic leukemia / Günter Henze and Arend von Stackelberg. B-cell acute lymphoblastic leukemia and Burkitt lymphoma / John T. Sandlund and Ian T. Magrath. Acute myeloid leukemia / Jeffrey E. Rubnitz, Bassem I. Razzouk, and Raul C. Ribeiro. Relapsed acute myeloid leukemia / Ursula Creutzig. Myelodysplastic syndrome / Henrik Hasle. Chronic myeloproliferative disorders / Charlotte M. Niemeyer and Franco Locatelli. Hematopoietic stem cell transplantation / Rupert Handgretinger, Victoria Turner, and Raymond Barfield. Acute leukemia in countries with limited resources / Raul C. Ribeiro, Scott C. Howard, and Ching-Hon Pui. Antibody-targeted therapy / Eric L. Sievers and Irwin D. Bernstein. Adoptive cellular immunotherapy / Helen E. Heslop and Cliona M. Rooney. Gene transfer: methods and applications / Martin Pulé and Malcolm K. Brenner. Minimal residual disease / Dario Campana, Andrea Biondi, and Jacques J.M. van Dongen -- Complications and supportive care. Acute complications / Scott C. Howard, Raul C. Ribeiro, and Ching-Hon Pui. Late complications after leukemia therapy / Melissa M. Hudson. Therapy-related leukemias / Carolyn A. Felix. Infectious disease complications in leukemia / Jeremy A. Franklin and Patricia M. Flynn. Hematologic supportive care / Fariba Navid and Victor M. Santana. Pain management / Alberto J. de Armendi and Doralina L. Anghelescu. Psychosocial issues / Raymond K. Mulhern, Sean Phipps, and Vida L. Tyc. Nursing care / Pamela S. Hinds, Jami S. Gattuso, and Belinda N. Mandrell.
Additional Edition:
Print version: ISBN 9780521825191
Language:
English
URL:
https://doi.org/10.1017/CBO9780511471001
