UID:
almahu_9949112306002882
Umfang:
1 online resource (various pagings) :
,
illustrations (some color).
ISBN:
9780750337397
,
9780750337380
Serie:
Biophysical Society-IOP series
Inhalt:
Diabetes Systems Biology provides senior undergraduate students and junior scientists, interested in diabetes systems biology, with a tool to learn more about the mathematical models and methods used to understand macroscopically and microscopically beta-cell behaviour in health and disease. The book introduces readers to the quantitative methods used to examine beta-cell dynamics, islet biology and architecture, as well as diabetes etiology and implications. The goal is to allow junior researchers in the fields of mathematical biology and biophysics to obtain a broad understanding of these quantitative methods, and guide them into taking the first steps into the field of diabetes systems biology. At the end of each chapter, several problem-solving exercises (that require both analytical and computational skills) are provided for the readers to help them become more proficient in this field. Part of Biophysical Society-IOP series.
Anmerkung:
"Version: 20201201"--Title page verso.
,
1. Introduction / Anmar Khadra -- part I. Beta-cell function. 2. An introduction to beta cell electrophysiology and modeling / Leslie S. Satin, Margaret Watts and Arthur S. Sherman -- 3. Recent advances in mathematical modeling and statistical analysis of exocytosis in endocrine cells / Morten Gram Pedersen, Francesco Montefusco, Alessia Tagliavini and Giuliana Cortese -- part II. Modeling islet biology. 4. Islet architecture / Junghyo Jo -- 5. Intra-islet network / Junghyo Jo and Margaret Watts -- 6. The role of islet cell network in insulin secretion / I. Johanna Stamper, Nathaniel Wolanyk and Xujing Wang -- part III. Insulin release in health and disease. 7. Insulin release in health and disease / Chiara Dalla Man and Morten Gram Pedersen -- part IV. Autoimmune type 1 diabetes. 8. Applying systems biology to the genetics of age-of-onset dependent heterogeneity in type 1 diabetes / Shouguo Gao, Nathaniel Wolanyk, Soumitra Ghosh and Xujing Wang -- 9. Immune-cell dynamics in type 1 diabetes / Hassan Jamaleddine and Anmar Khadra -- part V. Diabetes implications on kidneys. 10. Diabetes implications on kidneys / Anita T. Layton and Rui Hu.
,
Also available in print.
,
Mode of access: World Wide Web.
,
System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.
Weitere Ausg.:
Print version: ISBN 9780750337373
Weitere Ausg.:
ISBN 9780750337403
Sprache:
Englisch
DOI:
10.1088/978-0-7503-3739-7
URL:
https://iopscience.iop.org/book/978-0-7503-3739-7
