UID:
almahu_9949697619702882
Umfang:
1 online resource (509 p.)
ISBN:
0-85709-671-0
Serie:
Woodhead Publishing Series in Biomaterials ; Number 72
Inhalt:
Heart disease is the leading cause of death in the Western World and heart failure following a myocardial infarction continues to increase despite urgent revascularization. Cell therapy offered the promise to reverse cardiac injury and prevent heart failure, but the initial clinical trials were not as effective as anticipated. New approaches to restore ventricular function are urgently needed. Cardiac regeneration and repair Volume 2 reviews the use of biomaterials, alone or combined with cell therapy, to provide tissue engineered constructs to repair the injured heart and prevent or reverse h
Anmerkung:
Description based upon print version of record.
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Cover; Cardiac regeneration and repair: Volume 2: Biomaterials and tissue engineering; Copyright; Contents; Contributor contact details; Woodhead Publishing Series in Biomaterials; Foreword; Introduction; Part I Biomaterials for cardiac regeneration and repair; 1 Nanotechnology and nanomaterials for cardiac repair; 1.1 Introduction; 1.2 Electrospinning nanofibrous scaffolds; 1.3 Conductive nanomaterial for myocardial infarction (MI); 1.4 Nanomedicine; 1.5 Future trends; 1.6 References; 2 Hydrogels for cardiac repair; 2.1 Introduction; 2.2 Hydrogels
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2.3 Injectable hydrogels alone for cardiac repair2.4 Hydrogels as a platform for co-delivery; 2.5 Delivery strategies of hydrogels; 2.6 Future trends; 2.7 Sources of further information and advice; 2.8 References; 3 Injectable biomaterials for cardiac regeneration and repair; 3.1 Introduction; 3.2 Design criteria for biomaterials in cardiac tissue engineering; 3.3 Injectable biomaterials; 3.4 Bioactive molecules used in cardiac tissue engineering; 3.5 Hydrogels to promote endogenous cardiac regeneration and repair; 3.6 Hydrogels for the delivery of cells for cardiac regeneration
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3.7 Hydrogels for the artificial maintenance of ventricle geometry and repair3.8 Future trends; 3.9 References; 4 Biomaterials for enhancing endothelial progenitor cell (EPC) therapy for cardiac regeneration; 4.1 Introduction; 4.2 Endothelial progenitor cells (EPCs); 4.3 Enhancing EPC therapy; 4.4 Future trends; 4.5 Conclusion; 4.6 References; 5 Endothelial progenitor cell (EPC)-seeded intravascular stents; 5.1 Intravascular stents; 5.2 Endothelial progenitor cells (EPCs); 5.3 EPC-seeded intravascular stents; 5.4 Conclusion; 5.5 Sources of further information and advice; 5.6 References
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Part II Tissue engineering for cardiac regeneration and repair6 Biomaterials and cells for cardiac tissue engineering; 6.1 Introduction; 6.2 Cardiac structure; 6.3 Cardiac remodeling in myocardial infarction (MI); 6.4 Cells for cardiac tissue engineering; 6.5 Materials for cardiac tissue engineering; 6.6 Creation of heart tissue using cell and biomaterials: an in vitro approach; 6.7 Creation of heart tissue using cell andbiomaterials: an in vivo approach ofinjectable matrices; 6.8 Vascularization in myocardial tissue engineering; 6.9 Ventricular aneurysm repair using cells and biomaterials
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6.10 Clinical applications6.11 Conclusion and future trends; 6.12 References; 7 Decellularized biological scaffolds for cardiac repair and regeneration; 7.1 Introduction; 7.2 Methods of bioscaffold preparation; 7.3 Cardiac repair with non-cardiac bioscaffolds; 7.4 Tissue specificity of extracellular matrix bioscaffolds; 7.5 Current methods for decellularizing cardiac tissue; 7.6 Whole organ engineering; 7.7 References; 8 Biomaterial scaffolds for cardiac regeneration and repair derived from native heart matrix; 8.1 Heart failure and cardiac tissue engineering
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8.2 Extracellular matrix (ECM) as a biomaterial
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English
Weitere Ausg.:
ISBN 0-85709-659-1
Sprache:
Englisch
