Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Basel : Karger
    UID:
    b3kat_BV036069272
    Format: 1 Online-Ressource (XII, 170 Seiten) , Illustrationen, Diagramme
    ISBN: 9783318014419
    Series Statement: Progress in experimental tumor research Vol. 39
    Content: This book summarizes the current knowledge on how tumors interact with the nervous system and what impact this might have for the progression and treatment of cancer.It begins with an introduction to the organization and physiology of the nervous system, especially of the peripheral nervous system with its high degree of plasticity. Subsequent chapters discuss the interaction between peripheral nerves and tumor cells, the so-called neuro-neoplastic synapse, with regard to carcinogenesis, predictive tumor markers, tumor growth and tumor progression leading to metastasis. In this part, the concept of neoneurogenesis is postulated as a process by which the tumor regulates its own innervation through the release of neurotrophic factors, in analogy to the process of neoangiogenesis discovered three decades ago. Once nerve endings have grown into the tumor, these can release neurotransmitters which promote tumor cell migration and metastasis development. The final chapters reflect on the role of stem cells in neoneurogenesis and consider pharmacological approaches for the inhibition of neuro-neoplastic interactions as a basis for new anticancer therapies.Targeted primarily at investigators in experimental and clinical oncology, this book is also of special interest to neurobiologists as well as developmental and cell biologists
    Note: important implications for the progression and treatment of cancer
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-8246-9
    Language: English
    Subjects: Medicine
    RVK:
    Keywords: Krebszelle ; Peripheres Nervensystem ; Wechselwirkung ; Aufsatzsammlung
    Author information: Entschladen, Frank
    Author information: Zänker, Kurt S. 1946-
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. Further information can be found on the KOBV privacy pages