UID:
almafu_9958117853602883
Format:
1 online resource (127 pages) :
,
illustrations
Edition:
1st ed.
ISBN:
0-309-17405-8
,
1-280-18681-X
,
9786610186815
,
0-309-59183-X
,
0-585-02454-5
Note:
Bibliographic Level Mode of Issuance: Monograph
,
Antimicrobial Resistance: Issues and Options -- Copyright -- Preface -- THE FORUM -- THE REPORT AND ITS ORGANIZATION -- ACKNOWLEDGMENTS -- NOTES -- Contents -- Workshop Summary -- INTRODUTION -- ISSUSE AND OPTIONS -- Workshop Report -- INTRODUCTION -- The Topic -- The Workshop -- THE COSTS OF ANTIMICROBIAL RESISTANCE -- Background -- Recent Case Material -- TRACKING THE PROBLEM: CURRENT APPROACHES TO SURVEILLANCE -- Characteristics of an Ideal Resistance Surveillance System -- Local-Level Surveillance -- National Systems -- The United States Centers for Disease Control and Prevention -- The Surveillance Network -- The Canadian System -- The Icelandic Surveillance System -- International Systems -- CEM/NET -- World Health Organization (WHO) Initiatives -- SENTRY -- Surveillance and the Laboratory -- What Is Needed -- System Design Issues -- Funding for Surveillance -- HOW CAN THE SCIENCES HELP? -- Implications of Mapping the Genome -- Molecular Detection of Genes Associated with Antimicrobial Resistance -- Limitations of Phenotype-Based Detection Methods -- Knowledge About the Genetic Basis of Resistance -- Advantages and Limitations of Genotype-Based Antimicrobial Resistance Detection -- High-Density Oligonucleotide Arrays -- Applications of Genomics and Bioinformatics to the Development of Anti-Infectives -- A Role for New Therapeutic Approaches in Combating Antimicrobial Resistance -- Applications of Field Surveillance in the United States and Globally -- What Is Needed -- SOURCES OF RESISTANCE AND ANTIBIOTIC USE -- Sources of Resistance -- Antibiotic Use -- The Hospital -- The Community -- The Farm -- Factors in Inappropriate Use of Antibiotics -- Strategies for Judicious Antibiotic Use -- RESISTANCE AND FOOD PRODUCTION: ISSUES AND NEEDS -- Concerns and Perspectives from Producers -- A National Surveillance System.
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Strengthened Professional and Public Education -- Increased Research -- The Ecology of Resistance on the Farm -- U.S. Department of Agriculture -- U.S. Environmental Protection Agency -- Areas for Consideration and Action in Food Production -- Collaboration -- Research -- Education -- LEGAL AND REGULATORY CONCERNS -- Matters of Law and Possible Responses -- Surveillance -- Rational Use of Antimicrobial Drugs -- Research and Development -- Intellectual Property Protection -- New Products -- Existing Products and Compounds -- Targeted Drug Development -- Collaborative Research and Development -- Regulatory FDA Responses to Antimicrobial Resistance -- Restricted Distribution -- SUMMARY OF AREAS FOR CONSIDERATION -- Surveillance -- Information Systems -- Laboratory Systems -- Law and Regulation -- Response: Prolonging Effectiveness -- Education -- Law and Regulation -- Response: Developing New Products -- Incentives for Industry -- Research -- Education -- Agricultural Use -- Research -- FINAL COMMENTS -- NOTES -- APPENDIX A Inventory of Surveillance Systems -- DOMESTIC ANTIMICROBIAL SURVEILLANCE ACTIVITIES -- United States -- United States Military Surveillance -- United States: Regional Surveillance -- OTHER COUNTRIES -- Canada -- Denmark -- Finland -- Greece -- Iceland -- EUROPEAN-WIDE SYSTEMS -- GLOBAL SURVEILLANCE SYSTEMS -- APPENDIX B American Society for Microbiology Recommendations -- NATIONAL ANTIMICROBIAL SURVEILLANCE SYSTEM -- A.Indications -- B.Considerations -- 1. National surveillance system should do the following -- 2. Monitoring of organisms -- 3. Geographic locations of participants -- 4. Monitoring of populations -- 5. Methods -- 6. Locations of pathogen testing -- 7. Format for data -- 8. Data entry and analyses -- 9. Frequency of analysis and access -- 10. Organization of the surveillance system -- 11. Immediate recommendations.
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Appendix C Glossary and Acronyms -- Appendix D Workshop Agenda.
,
English
Additional Edition:
ISBN 0-309-06084-2
Language:
English
