UID:
almafu_9959088570202883
Format:
1 online resource (306 pages)
ISBN:
0-12-817019-0
,
0-12-817018-2
Series Statement:
Issn ; v.Volume 152
Content:
Three-Dimensional Electron Microscopy of Macromolecular Assemblies is the first systematic introduction to single-particle methods of reconstruction. It covers correlation alignment, classification, 3D reconstruction, restoration, and interpretation of the resulting 3D images in macromolecular assemblies. It will be an indispensable resource for newcomers to the field and for all using or adopting these methods. Key Features * Presents methods that offer an alternative to crystallographic techniques for molecules that cannot be crystallized * Describes methods that have been instrumental in exploring the three-dimensional structure of * the nuclear pore complex * the calcium release channel; * the ribosome * chaperonins.
Note:
Introduction. -- Electron Microscopy of Macromolecular Assemblies. -- Two-Dimensional Averaging Techniques. -- Multivariate Statistical Analysis and Classification of Images. -- Three-Dimensional Reconstruction. -- Interpretation of Three-Dimensional Images of Macromolecules. -- Example for an Apllication: Calcium Release Channel. -- Appendices.
Language:
English
Keywords:
Index not Present.
;
Index not Present.
