UID:
edoccha_9960074047102883
Format:
1 online resource (570 p.)
ISBN:
1-4832-1726-4
Content:
Modulation by Covalent Modification
Note:
Description based upon print version of record.
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Front Cover; Modulation by Covalent Modification; Copyright Page; Table of Contents; Contributors; Foreword; Preface; Thressa C. Stadtman; Earl R. Stadtman; Part I: Principles of Coordination and Amplification; Chapter 1. Cyclic Cascade Systems in Metabolic Regulation; I. Historical Account; II. Cyclic Cascade Model; III. Experimental Verification of the Model; IV. ATP Flux in Cyclic Cascade Systems; V. Concluding Remarks; REFERENCES; Chapter 2. Sensitivity of Metabolic Fluxes to Covalent Control; I. Introduction; II. Flux through the Glyoxylate Shunt; III. IDH Kinase/Phosphatase
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IV. Branch-Point ParametersV. Determination of Fluxes; VI. Correlation between in Vitro and in Vivo Velocities; VII. Regulatory Transitions; VIll. The Branch-Point Effect: Sensitivity to Control; IX. Conclusions; ACKNOWLEDGMENTS; REFERENCES; Chapter 3. The Coordinated Control of Metabolic Pathways by Broad-Specificity Protein Kinases and Phosphatases; I. Introduction; II. Cyclic AMP-Dependent Protein Kinase; III. Calmodulin-Dependent Multiprotein Kinase; IV. Protein Phosphatases Involved in Cellular Regulation; V. Ca2+-Calmodulin-Dependent Protein Phosphatase 2B; ACKNOWLEDGMENTS; REFERENCES
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Part II: Phosphorylation and DephosphorylationChapter 4. Regulation of Mammalian Pyruvate and Branched-Chain α-Keto Acid Dehydrogenase Complexes by Phosphorylation-Dephosphorylation; I. Introduction; II. Pyruvate Dehydrogenase Complex; III. α-Ketoisovalerate Dehydrogenase Complex; ACKNOWLEDGMENTS; REFERENCES; Chapter 5. The Mechanism of Regulation of Smooth Muscle Myosin by Phosphorylation; I. Myosin Phosphorylation and Mg-ATPase; II. Regulation of the Actomyosin Kinetic Cycle by Phosphorylation; III. Interaction of Myosin Heads during Phosphorylation; REFERENCES
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Chapter 6. Protein Phosphorylation and Translational Control in Reticulocytes: Activation of the Heme-Controlled Translational Inhibitor by Calcium Ions and PhospholipidI. Introduction: Translational Regulation in Reticulocytes; II. Mechanism of Translational Inhibition by elF-2α Kinases; III. Activation of elF-2α Kinases; IV. Activation of HCI by Ca2+ and Phospholipid; V. Studies on the Mechanism of the Ca2+-Phospholipid Activation of HCI; VI. Discussion; VII. Summary; ACKNOWLEDGMENT; REFERENCES
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Chapter 7. Insulin-Dependent Tyrosine Protein Kinase: Cellular Distribution and Copurification with the Insulin ReceptorI. Evidence for Immunological and Biochemical Conservation of the Insulin Receptor in a Variety of Tissues; II. Copurification of the Insulin Receptor and Insulin-Dependent Tyrosine Protein Kinase from Human Placenta; III. Evidence that Phosphorylation Alters the Enzymatic Properties of the Receptor; ACKNOWLEDGMENT; REFERENCES; Chapter 8. Insulin-Stimulated Phosphorylation of Actin by Human Placental Insulin Receptor Preparations; I. Introduction; II. Materials and Methods
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III. Results
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English
Additional Edition:
ISBN 1-322-34040-4
Additional Edition:
ISBN 0-12-152827-8
Language:
English
