UID:
edoccha_9961042656702883
Format:
1 online resource (446 pages)
ISBN:
0-323-98814-8
,
0-323-98627-7
Content:
Substance Use and Addiction Research: Methodology, Mechanisms, and Therapeutics is an up-to-date, comprehensive, practical book on research methodologies for substance use and addiction that is intended for researchers and consumers of research information at all levels. The book is divided into four major sections, including an Introduction, Research Methodology for clinical trials, animal research and retrospective studies, Mechanisms of Use and Addiction, and Investigative Therapeutics: Designing and Measuring Outcomes. It serves a source for addressing all aspects of research design, methods and analysis within the context of the field of opioids, alcohol and other substances. The book covers what is known in the field of quantitative and qualitative research methods, provides future directions, and introduces new models for investigation. It is organized around a translational science framework, with the contents addressing substance use/addiction research in the context of epidemiology, etiology, intervention efficacy and effectiveness, and implementation of evidence-informed interventions.
Note:
Basics of Research Methodology -- 1. Reliability and validity in substance abuse and addiction research -- 2. Animal models -- 3. Translational research strategies -- 4. Experimental design in clinical trials -- Part 15. Experimental design in clinical trials -- Part 26. Qualitative and quantitative methods -- 7. Ethical issues in opioids, alcohol, other drugs and addiction-related research: -- 8. Informatics -- 9. Artificial intelligence and machine learning -- 10. Epidemiology and health services research methods -- 11. Imaging -- 12. Systematic review and meta-analysisMechanisms of abuse and addiction -- 13. Abuse and addiction -- 14. Assessment of addiction/pain and neurobiology -- 15. Physiological considerations in opioid addiction -- 16. Basic pharmacology - opioid substances -- 17. Basic pharmacology - non-opioid substances -- 18. Types of addiction19. Substance use -- 20. Special study populationsInvestigative Therapeutics: Designing studies and measuring outcomes -- 21. General therapy strategies in substance addiction -- 22. Alternative Therapy Strategies in Addiction -- 23. Drug testing and adherence monitoring -- 24. Pharmacogenetics - Genes, genetics, genomics and epigenetics -- 25. Novel therapeutic strategies effectiveness26. Methods of psychosocial interventions -- 27. Principles of vaccine development -- 28. Drug policy analysis -- 29. Implementation science: Theories, models and frameworks -- 30. Designing and testing population-based prevention programs -- 31. New vistas in research.
Language:
English
