UID:
edocfu_9958114318402883
Format:
1 online resource (269 p.)
Edition:
First edition.
ISBN:
1-281-02353-1
,
9786611023539
,
0-08-052454-0
Content:
Up-to-date review on the chemistry and biology of nucleosides Modern synthetic methodology Comprehensive coverage of antiviral nucleosides This book summarizes the recent advances in nucleosides chemistry and chemotherapy over the past 10-15 years. It covers recently discovered nucleoside antiviral agents, their therapeutic aspects and biochemistry, and also extensive reviews on their chiral synthesis.
Note:
Description based upon print version of record.
,
Front Cover; ANTIVIRAL NUCLEOSIDES: CHIRAL SYNTHESIS AND CHEMOTHERAPY; Copyright Page; Preface; Contents; Chapter 1. Recent Advances in Antiviral Nucleosides; 1.1. Introduction; 1.2. Structural features of nucleosides as antiviral agents; 1.3. 2'-Deoxy nucleosides and related analogs; 1.4. 2',3 '-Dideoxy nucleosides and related analog; 1.5. 2',3 '-Unsaturated nucleosides and related analog; 1.6. Nucleosides with a heterocyclic sugar ring moiety; 1.7. 3- or 4-Membered ring nucleosides; 1.8. Acyclonucleosides; 1.9. Ribofuranosyl nucleosides; 1.10. References
,
Chapter 2. Chiral Synthesis of Antiviral Nucleosides from Carbohydrate Templates2.1. Introduction; 2.2. 4'-Thiofuranose nucleosides; 2.3. Iso- and apio nucleosides; 2.4. Oxathiolane and dioxolane nucleosides; 2.5. Cyclopentyl carbocyclic nucleosides; 2.6. Cyclopropyl carbocyclic nucleosides; 2.7. C-Nucleosides; 2.8. Fluorinated nucleosides; 2.9. Acyclonucleosides; 2.10. Miscellaneous nucleosides; 2.11. References; Chapter 3. Oxathiolane and Dioxolane Nucleosides: Synthesis and Antiviral Activity; 3.1. Introduction; 3.2. Oxathiolane nucleosides; 3.3. Dioxolane nucleosides; 3.4. References
,
English
Additional Edition:
ISBN 0-444-51319-1
Language:
English
