UID:
almafu_9958126600102883
Format:
1 online resource (344 p.)
ISBN:
1-299-47282-6
,
0-323-15501-4
Series Statement:
Cell biology : a series of monographs
Content:
Drugs and the Cell Cycle
Note:
Description based upon print version of record.
,
Front Cover; Drugs and the Cell Cycle; Copyright Page; Table of Contents; List of Contributors; Preface; Chapter 1. Perspectives on Drugs and the Cell Cycle; I. Chemotherapy and the Cell Cycle; II. The Cell Cycle as a Sensitive Indicator for Drug Analysis; References; Chapter 2. Macromolecular Assembly Inhibitors and Their Action on the Cell Cycle; I. Introduction; II. Colchicine; III. Vinblastine; IV. Cytochalasin and Microfilaments; References; Chapter 3. The Effect of Mercuric Compounds on Dividing Cells; I. Introduction; II. Mercaptide Formation by Mercurials
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III. Production of c-Mitotic Figures by OrganomercurialsIV. Mercuric Compounds and the Generation Time, DNA and Protein Synthesis, the Cell Cycle, and Cilia Regeneration in Tetrahymena pyriformis; V. Distribution of-Methylmercuric Chloride in Fertilized Eggs of Lytechinus pictus; VI. Observations on the Structural Organization of Tetrahymena pyriformis Treated with Mercuric Chloride; VII. Concluding Remarks; References; Chapter 4. Adrenergic Drugs on the Cell Cycle; I. Introduction; II. Experimental Results; III. Discussion and Summary; References
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Chapter 5. Action of Narcotic and Hallucinogenic Agents on the Cell CycleI. Introduction; II. The Chemistry of Selected Drugs; III. Action of Drugs on Prokaryotic Cells; IV. Action of Drugs on Eukaryotic Cells; V. Present Studies on Tetrahymena; VI. Concluding Remarks; References; Chapter 6. Effects of Drugs on Hepatic Cell Proliferation Abbreviations; I. Introduction; II. Kinetics of Hepatic Cell Proliferation; III. Regulation of Hepatic Cell Proliferation; IV. Drugs and Hepatic Cell Proliferation; V. Concluding Remarks; References
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Chapter 7. Effects of Mitogens on the Mitotic Cycle: A Biochemical Evaluation of Lymphocyte ActivationI. Introduction; II. Background: Peripheral Blood Lymphocytes; III. Nature of Mitogenic Substances; IV. General Characteristics of Mitogen-Induced Lymphocyte Growth; V. Biochemical Events in Lymphocyte Transformation; VI. Discussion and Conclusions; References; Chapter 8. Intestinal Cytodynamics: Adductions from Drug Radiation Studies; I. Introduction; II. Nature of the Crypt Progenitor Cell; III. Factors Influencing Intestinal Tolerance to Cytotoxins
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IV. Control Aspects of Intestinal Cell RenewalV. Summary; References; Chapter 9. The Effects of Antitumor Drugs on the Cell Cycle; I. Introduction; II. Antitumor Drugs; III. General Discussion; IV. Summary; References; Chapter 10. Effects of Purines, Pyrimidines, Nucleosides, and Chemically Related Compounds on the Cell Cycle; I. Introduction; II. Biochemical Mechanisms of Agents; III. Effect of Agents on Cells; IV. Correlation of Biochemical Effects and Effects on the Cell Cycle; V. Examples of the Logic and Use of These Agents for Cancer Chemotherapy; VI. Concluding Comments; References
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AUTHOR INDEX
,
English
Additional Edition:
ISBN 0-12-781260-1
Language:
English
