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  • 1
    UID:
    edocfu_9959327406502883
    Format: 1 online resource (xviii, 385 pages) : , illustrations, portraits
    ISBN: 9783527651085 , 352765108X , 9783527651115 , 352765111X , 9781299241206 , 1299241204
    Content: "Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a continuation of the successful book series with new examples of established and recently introduced drugs. The major part of the book is written by key inventors either as a case study or a study of an analogue class. With its wide range across a variety of therapeutic fields and chemical classes, this is of interest to virtually every researcher in drug discovery and pharmaceutical chemistry, and--together with the previous volumes--constitutes the first systematic approach to drug analogue development"--Publisher's website.
    Note: General Aspects. Pioneer and Analogue Drugs / , Competition in the Pharmaceutical Drug Development / , Metabolic Stability and Analogue-Based Drug Discovery / , Use of Macrocycles in Drug Design Exemplified with Ulimorelin, a Potential Ghrelin Agonist for Gastrointestinal Motility Disorders / , Drug Classes. The Discovery of Anticancer Drugs Targeting Epigenetic Enzymes / , Thienopyridyl and Direct-Acting P2Y Receptor Antagonist Antiplatelet Drugs / , Selective Estrogen Receptor Modulators / , Discovery of Nonpeptide Vasopressin V2 Receptor Antagonists / , The Development of Cysteinyl Leukotriene Receptor Antagonists / , Case Studies. The Discovery of Dabigatran Etexilate / , The Discovery of Citalopram and Its Refinement to Escitalopram / , Tapentadol : From Morphine and Tramadol to the Discovery of Tapentadol / , Novel Taxanes: Cabazitaxel Case Study / , Discovery of Boceprevir and Narlaprevir: A Case Study for Role of Structure-Based Drug Design / , A New-Generation Uric Acid Production Inhibitor: Febuxostat /
    Additional Edition: Print version: Analogue-based drug discovery III. Weinheim : Wiley-VCH, [2013] ISBN 9783527330737
    Language: English
    Keywords: Electronic books.
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