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  • 1
    Online Resource
    Online Resource
    Cambridge ; : Cambridge University Press,
    UID:
    edocfu_9960117190002883
    Format: 1 online resource (xiii, 272 pages) : , digital, PDF file(s).
    ISBN: 1-107-15420-0 , 1-281-21796-4 , 9786611217969 , 0-511-16870-5 , 0-511-16771-7 , 0-511-16913-2 , 0-511-31456-6 , 0-511-54520-7 , 0-511-16825-X
    Content: Originally published in 2006, this book provides an in-depth account of trophoblast: the tissue derived from the fertilised egg that nourishes and protects the developing fetus. The cells of the trophoblast have many unique qualities, and exhibit great variability across different species. It has a fascinating role in the development of the placenta and as a regulator during early growth of the embryo. These aspects are all fully covered as well as studies on why it is not rejected by the mother as 'foreign' tissue. Disorders of trophoblast during development also manifest themselves in several clinical conditions during pregnancy, including gestational trophoblastic disease and pre-eclampsia. From stem cells through to epigenetics, implantation and X-chromosome inactivation, there is a lot to be learned about trophoblast, this volume provides a detailed summary of knowledge regarding the subject.
    Note: Title from publisher's bibliographic system (viewed on 05 Oct 2015). , Cover; Half-title; Title; Copyright; Contents; Contributors; Participants; Preface; Chair's introduction; 1 Trophoblast cell fate specification; 2 Stem cells: pluripotency and extraembryonic differentiation in the mouse; 3 Epigenetic regulation of trophoblast development; 4 Regulation of X-chromosome inactivation in relation to lineage allocation in early mouse embryogenesis; General discussion I; 5 Gestational trophoblastic disease; 6 Trophoblast and the first trimester environment; 7 Implantation is a sticky situation; 8 Trophoblast regulation of maternal endocrine function and behaviour , General discussion II9 Molecular signalling in embryo-uterine interactions during implantation; 10 Trophoblast and pre-eclampsia; 11 Trophoblast and uterine mucosal leukocytes; 12 Immunology of trophoblast: a reappraisal; Final general discussion; Index , English
    Additional Edition: ISBN 1-107-40315-4
    Additional Edition: ISBN 0-521-85165-3
    Language: English
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