Format:
Online-Ressource (digital)
ISBN:
9783764385613
Series Statement:
SpringerLink
Content:
Serotonin and Sleep: Molecular, Functional, and Clinical Aspects covers the complete spectrum of the field and explores the link between the latest basic molecular, functional, and clinical aspects of serotonin and the practice of sleep medicine. The volume focuses on 24 different areas of research, with special emphasis relating the state of basic and clinical research to potential applications: changing concepts in serotonin research, topographic organization and chemoarchitecture, receptor mechanisms - its organization and regulation of behavioral states, electrophysiological mechanisms - i
Note:
Includes bibliographical references and index
,
Contents; List of contributors; Glossary; Dedication; Credits and acknowledgements; Foreword by Philip J. Cowen; Preface; Evolution of concepts; Changing concepts on the role of serotonin in the regulationof sleep and waking; The dorsal raphe nucleus and median raphe nucleus: organization and projections; Topographic organization and chemoarchitecture of the dorsal raphenucleus and the median raphe nucleus; Efferent and afferent connections of the dorsal and median raphenuclei in the rat
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Reciprocal connections between the suprachiasmatic nucleus andthe midbrain raphe nuclei: A putative role in the circadian controlof behavioral statesSerotonin receptors; Localization of 5-HT receptors in the mammalian cortex; Molecular biology of 5-HT receptors; Electrophysiology of serotonergic neurons and the regulation of serotonin release; Brain serotonergic neuronal activity in behaving cats; Electrophysiological studies on serotonergic neurons and sleep; Role and origin of the GABAergic innervationof dorsal raphe serotonergic neurons
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Regulation of serotonin release by inhibitoryand excitatory amino acidsNeuphysiological aspects of the regulation of serotonin neurons by the orexinergic system; Serotonin receptors and the regulation of behavioural state; Serotonin and dreaming; Involvement of the 5-HT 1A and the 5-HT 1B receptor in the regulationof sleep and waking; Mechanisms involved in the inhibition of REM sleep by serotonin; Effect of 5-HT 2A/2B/2C receptor agonists and antagonists on sleepand waking in laboratory animals and humans; Effect of the selective activation of serotonin 5-HT 3 receptorson sleep and waking
,
5-HT 7 receptor modulation of sleep patternsSleep and waking in mutant mice that do not express various proteinsinvolved in serotonergic neurotransmission such as the serotonergictransporter, monoamine oxidase A, and 5-HT 1A , 5-HT 1B , 5-HT 2A ,5-HT 2C and 5-HT 7 receptors; Circadian control by serotonin and melatonin receptors:Clinical relevance; Serotonergic mechanisms contributing to arousal and alerting; Relevance of serotonin to clinical disorders and drug actions; Contribution of chemosensitive serotonergic neurons to interactionsbetween the sleep-wake cycle and respiratory control
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Obstructive sleep apnea:The potential for serotonergic pharmacotherapiesThe effects of antidepressant drugsand 5-HT 1A agonists on human sleep; The effect of typical and atypical antipsychotic drugson sleep of schizophrenic patients; Subject Index
Additional Edition:
ISBN 9783764385606
Additional Edition:
Buchausg. u.d.T. Serotonin and sleep: molecular, functional and clinical aspects Basel : Birkhäuser, 2008 ISBN 9783764385606
Additional Edition:
ISBN 376438560X
Language:
English
Subjects:
Biology
Keywords:
Serotonin
;
Schlaf
;
Serotonin
;
Schlaf
;
Neuropharmakologie
;
Aufsatzsammlung
DOI:
10.1007/978-3-7643-8561-3
URL:
Volltext
(lizenzpflichtig)
Author information:
Nutt, David J. 1951-
Author information:
Pandi-Perumal, Seithikurippu R. 1964-
