Umfang:
Online-Ressource (XXXVI, 424p. 65 illus. in color, digital)
Ausgabe:
1
ISBN:
9781441966124
Serie:
Advances in Experimental Medicine and Biology 691
Inhalt:
The biennial TNF-family conferences have been held over the past 20 years, from the time that TNF was cloned. These meetings have followed the enormous progress in this field. Much is now known about the members of the TNF ligand and receptor families, their signaling proteins, mechanisms of action and cellular functions. This volume is the proceedings of the 12th TNF International Conference, held in April 2009. This conference focuses on the physiological, pathophysiological, and medical significance of these important regulators. Sessions at the meeting specifically address their involvement in immunity, development, apoptosis, autoimmunity, cancer, and infection, the normal function and pathology of the neuronal system, as well as major unresolved questions about their mechanisms of action.
Anmerkung:
Description based upon print version of record
,
Preface by David Wallach; Preface by Marc Feldmann; Contents; Contributors; Part I Roles of the TNF Family in Tissue Homeostasis and Normal Development; Part II Novel Aspects of Signaling Activation by the TNF Family: Novel Aspects of the Functions of the TRAFs and cIAPs; Part III Novel Aspects of Signaling Activation by the TNF: Ubiquitin Modification of Signaling Proteins; Part IV Novel aspects of Signaling Activation by the TNF Family: TNF Signaling and Gene Regulatory Networks
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Part V Roles of the TNF Family in Infectious Diseases and Interrelationship of the TNF Family and Pattern Recognition Receptor Signaling: Roles of the TNF Family in Infectious DiseasesPart VI Roles of the TNF Family in Infectious Diseases and Interrelationship of the TNF Family and Pattern Recognition Receptor Signaling: Interrelationship of the TNF Family and Pattern Recognition R; Part VII Novel Aspects of Immune Regulation by the TNF Family; Part VIII Control of Lymphocyte Function and Repertoire by the TNF Family
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Part IX Advances in Applying Our Knowledge to Therapy: Mechanisms of Pathological and Therapeutic Effects of the TNF FamilyPart X Advances in Applying our Knowledge to Therapy: Rational Design of New Means for Therapeutic Modulation of Function of the TNF Family; Part XI Roles of the TNF Family in Neuronal Development, Function, and Pathology; Part XII Cell Death Mechanisms Controlled by the TNF Family; Appendix I: Contributors to Abstracts of Talks and Posters at the 12th TNF Conference; Appendix II: Abstracts of Talks and Posters Presented at the 12th TNF Conference; Subject Index;
Weitere Ausg.:
ISBN 9781441966117
Weitere Ausg.:
Erscheint auch als Druck-Ausgabe Advances in TNF family research New York, NY [u.a.] : Springer, 2011 ISBN 9781441966117
Weitere Ausg.:
ISBN 9781441966124
Sprache:
Englisch
DOI:
10.1007/978-1-4419-6612-4
URL:
Volltext
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