Umfang:
1 online resource (471 pages)
ISBN:
9781351679909
Inhalt:
Cover -- Half Title -- Title Page -- Copyright Page -- Table of Contents -- Acronyms and Abbreviations -- List of Boxes -- Preface -- Acknowledgements -- Introduction -- Part I Background -- Chapter 1 Vaccines -- 1.1 A Brief History of Vaccines -- 1.2 Vaccine Antigens, Platforms and Excipients -- 1.2.1 Vaccine Antigens -- 1.2.2 Vaccine Platforms -- 1.2.3 Adjuvants -- 1.2.4 Other Vaccine Excipients -- 1.3 Vaccine Potency, Stability, Immunogenicity and Safety -- 1.4 Routes of Administration of Vaccines -- 1.5 Vaccine Trials and Licensure of Vaccines -- 1.6 Vaccine Manufacturing -- Summary -- References -- Chapter 2 How Vaccines Work: Immune Responses and Vaccine Failure -- 2.1 The Immune System -- 2.2 The Humoral Immune Response: Antibodies -- 2.3 Cell-Mediated Immunity -- 2.4 Systemic and Mucosal Immunity -- 2.5 Implications of Mucosal and Systemic Immunity to Prevent Infection and Infectiousness -- 2.6 Persistence of Immunity -- 2.7 Determinants of the Immune Response to Vaccination and Its Persistence -- 2.8 Assessing the Immune Response to Vaccination -- 2.9 Vaccine Failure -- Summary -- References -- Chapter 3 Vaccination Programmes: Aims and Strategies -- 3.1 History of Vaccination Programmes -- 3.2 Goals, Aims and Targets of Vaccination Programmes -- 3.3 Vaccination Programme Strategies: Universal Or Selective Vaccination -- 3.4 Delivery of Universal Vaccination Programmes: Routine, Supplemental and Ring Vaccination -- 3.5 Vaccination Schedules -- 3.6 Vaccine Policy -- 3.7 Monitoring and Evaluation of Vaccination Programmes -- 3.8 Modifying Vaccination Programmes -- Summary -- References -- Chapter 4 Dynamics of Vaccine-Preventable Infectious Diseases -- 4.1 Contact, Transmission, Herd Immunity and Epidemic Cycles -- 4.2 Reproduction Numbers and the Critical Immunisation Threshold.
Anmerkung:
Description based on publisher supplied metadata and other sources
Weitere Ausg.:
ISBN 9781138054844
Weitere Ausg.:
Erscheint auch als Druck-Ausgabe ISBN 9781138054844
Sprache:
Englisch
