Format:
1 online resource (532 pages)
ISBN:
9783030447663
Content:
Intro -- Foreword -- Preface -- Contents -- Contributors -- I: Biology and Scar Formation -- 1: Fetal Wound Healing -- 1.1 Background -- 1.2 Inflammation -- 1.3 Extracellular Matrix -- 1.4 Angiogenesis -- 1.5 Keratinocytes -- 1.6 Fibroblasts -- 1.7 Mechanical Forces -- 1.8 Remodeling -- 1.9 Skin Appendix Formation -- 1.10 Conclusions -- References -- 2: Mechanobiology of Cutaneous Scarring -- 2.1 Background -- 2.2 Role of Mechanobiology in Cutaneous Scarring -- 2.3 Cellular and Tissue Responses to Mechanical Forces -- 2.4 Role of Mechanobiology in the Development of Pathological Scars -- 2.5 A Pathological Scar Animal Model that Is Based on Mechanotransduction -- 2.6 Mechanotherapy for Scar Prevention and Treatment -- 2.6.1 Stabilization Materials -- 2.6.2 Sutures -- 2.6.3 Z-Plasty, Skin Grafting, and Local Flaps -- 2.7 Conclusion -- References -- 3: Scar Formation: Cellular Mechanisms -- 3.1 Background -- 3.2 Introduction -- 3.3 General Mechanisms of Scar Formation -- 3.4 Morphological and Biochemical Characteristics of Myofibroblast Phenotype -- 3.5 Cellular Origins of Myofibroblasts -- 3.6 Regulation of Myofibroblast Phenotype -- 3.7 Role of Myofibroblasts in Pathological Scarring and Fibrosis -- 3.8 The Role of Mechanical Tension -- 3.9 Role of Innervation in Skin Healing -- 3.10 Therapeutic Options -- 3.11 Conclusion -- References -- II: Epidemiology of Scars and Their Consequences -- 4: The Epidemiology of Keloids -- 4.1 Background -- 4.2 Demographic Risk Factors That Shape Keloid Rates -- 4.3 Genetic Risk Factors That Shape Keloid Rates -- 4.4 Environmental Risk Factors That Shape Keloid Rates -- 4.5 Conclusion -- References -- 5: Epidemiology of Scars and Their Consequences: Burn Scars -- 5.1 Burn Injuries and Their Treatment -- 5.1.1 Burn Care -- 5.1.2 Acute Phase.
Note:
Description based on publisher supplied metadata and other sources
Additional Edition:
ISBN 9783030447656
Additional Edition:
Erscheint auch als Druck-Ausgabe ISBN 9783030447656
Language:
English
