Format:
1 Online-Ressource (viii, 97, xi Seiten, 5000 KB)
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Illustrationen, Diagramme
Content:
This dissertation aimed to determine differential expressed miRNAs in the context of chronic pain in polyneuropathy. For this purpose, patients with chronic painful polyneuropathy were compared with age matched healthy patients. Taken together, all miRNA pre library preparation quality controls were successful and none of the samples was identified as an outlier or excluded for library preparation. Pre sequencing quality control showed that library preparation worked for all samples as well as that all samples were free of adapter dimers after BluePippin size selection and reached the minimum molarity for further processing. Thus, all samples were subjected to sequencing. The sequencing control parameters were in their optimal range and resulted in valid sequencing results with strong sample to sample correlation for all samples. The resulting FASTQ file of each miRNA library was analyzed and used to perform a differential expression analysis. [...]
Note:
Dissertation Universität Potsdam 2023
Additional Edition:
Erscheint auch als Druck-Ausgabe Pellegrino, Antonio miRNA profiling for diagnosis of chronic pain in polyneuropathy Potsdam, 2023
Language:
English
Keywords:
Hochschulschrift
DOI:
10.25932/publishup-58385
URN:
urn:nbn:de:kobv:517-opus4-583858
Author information:
Seitz, Harald 1969-
