Format:
Online-Ressource
,
v.: digital
Edition:
Online-Ausg. Springer eBook Collection. Biomedical and Life Sciences Electronic reproduction; Available via World Wide Web
ISBN:
9783642128639
Series Statement:
Microbiology Monographs 17
Content:
Parasitic protozoa, including some which are agents of human and veterinary diseases, display special cytoplasmic structures and organelles. Metabolic pathways have been discovered in these organelles which open up new possibilities for drug targets. This work presents reviews dealing with cytoskeletal structures such as the mastigont system found in trichomonads, the sub-pellicular microtubules in trypanosomatids and the paraflagellar rod. Further chapters cover structures involved in the synthesis, secretion and uptake of molecules, including the flagellar pocket of trypanosomatids, the reservosome of Trypanosoma and the megasome found in Leishmania, the traffic of vesicles in Entamoeba histolytica, secretory organelles and the secretory events of intestinal parasites during encystation. Reviews on special organelles, such as the kinetoplast-mitochondrion complex, the apicoplast found in Apicomplexa, the glycosomes in Kinetoplastida and the acidocalcisomes found in several protozoa complete the volume.
Note:
Includes bibliographical references and index
,
Structures and Organelles in Pathogenic Protists; Preface; Reference; 1 Introduction; Contents; Contributors; The Mastigont System in Trichomonads; 1 Introduction; 2 The Mastigont System; 2.1 Basal Bodies and Associated Filaments; 2.1.1 Basal Body (kinetosomes); 2.1.2 Kinetosome R; 2.1.3 Kinetosomes #1, #2, #3, #4; 2.1.4 Clockwise Filaments; 2.1.5 Sigmoidal Filaments; 2.1.6 Supra-Kinetosomal Body or Supra-Basal Body; 2.1.7 Infra-Kinetosomal Body or Infra-Basal Body; 2.1.8 Marginal Lamella; 2.2 Costa; 2.2.1 Structure; 2.2.2 Types of Costa; 2.2.3 Association with Other Structures
,
2.2.4 Function and Motility2.2.5 Chemical Composition; 2.3 Comb; 2.4 Axostyle and Pelta; 2.4.1 Structure; 2.4.2 Pelta; 2.4.3 Functions; 2.4.4 Stability; 2.4.5 Movement; 2.4.6 Composition; 2.4.7 Association with Other Cell Structures; 2.5 The Parabasal Filaments; 2.6 Flagella; 2.6.1 The Undulating Membrane; 2.6.2 Flagellar Structure; 2.6.3 Flagellar Movement; 2.6.4 Flagellum Internalisation; 3 The Spindle; 3.1 The Atractophore; 4 Centrin; 5 Genome Sequence; References; Subpellicular Microtubules in Apicomplexa and Trypanosomatids; 2 Subpellicular Microtubules; 2.1 In Trypanosomatids
,
2.2 In Apicomplexans3 Visualization of the Whole Network of Subpellicular Microtubules; 3.1 In Trypanosomatids; 3.2 In Apicomplexans; 4 High-Resolution Images of the Microtubules; 4.1 In Trypanosomatids; 4.2 In Apicomplexa; 5 Immunocytochemical Characterization of the Microtubules; 5.1 In Trypanosomatids; 5.2 In Apicomplexa; 6 Biochemistry; 6.1 In Trypanosomatids; 7 Drug Sensitivity; 7.1 In Trypanosomatids; 7.2 In Apicomplexa; 8 Microtubule-Microtubule and Microtubule-Plasma Membrane Associations; 8.1 In Trypanosomatids; 8.2 In Apicomplexa; 8.3 The Conoid in Apicomplexa; 9 In Trypanosomatids
,
10 In Apicomplexans11 Functional Data; 11.1 In Trypanosomatids; 11.2 In Apicomplexans; 12 Perspectives; References; Flagellum Structure and Function in Trypanosomes; 1 Introduction; 2 The Structure of the Flagellum; 3 The Basal Body; 3.1 The Transition Zone; 3.2 The Axoneme; 3.3 The Paraflagellar Rod; 4 Flagellar Positioning and Adhesion; 5 Flagellum Construction; 5.1 Trypanosome Cell Cycle; 5.2 Intraflagellar Transport; 6 Functions of a Motile Flagellum; 6.1 Characteristics of Flagellum Motility; 6.2 Flagellum Motility Contributes to Completion of Cell Division
,
6.3 Motility and Clearance of Surface Proteins7 Conclusions and Perspectives; References; The Flagellar Pocket of Trypanosomatids: A Critical Feature for Cell Morphogenesis and Pathogenicity; 1 Introduction; 2 Physical Architecture of the Flagellar Pocket; 2.1 New Insights Provided by Electron Tomography; 3 Physical Organisation of the Flagellar Pocket and Dynamics of Operation; 3.1 Entry of Macromolecules into the Flagellar Pocket: The ``Neck Channel´´; 3.2 Membrane Domains and Boundaries Within the Flagellar Pocket; 4 The Role of the Flagellar Pocket in Immune Evasion
,
5 Life Cycle Differences in Size and Function of the Flagellar Pocket
,
Electronic reproduction; Available via World Wide Web
Additional Edition:
ISBN 9783642128622
Additional Edition:
Buchausg. u.d.T. Structures and organelles in pathogenic protists Berlin : Springer, 2010 ISBN 9783642128622
Language:
English
Keywords:
Protozoen
;
Pathogener Mikroorganismus
;
Zellskelett
;
Organell
;
Protozoen
;
Pathogener Mikroorganismus
;
Zellskelett
;
Organell
;
Aufsatzsammlung
DOI:
10.1007/978-3-642-12863-9
URL:
Volltext
(lizenzpflichtig)
