Umfang:
XVII, 370 S.
,
Ill., graph. Darst.
ISBN:
9780470261231
Serie:
Wiley series on technologies for the pharmaceutical industry
Anmerkung:
Literaturangaben
,
Introduction to systems biology in drug discovery and developmentMethods for in silico biology : model construction and analysis -- Methods in in silico biology : modeling feedback dynamics in pathways -- Simulation of population variability in pharmacokinetics -- Applications of systems biology approaches to target identification and validation in drug discovery -- Lead identification and optimization -- The role of core biological motifs in dose-response modeling : an example with switch-like circuits -- Mechanism based pharmacokinetic-pharmacodynamic modeling during discovery and early development -- Developing oncology drugs using virtual patients of vascular tumor diseases -- Systems modeling applied to candidate biomarker identification -- Simulating clinical trials -- Pathway analysis in drug discovery -- Functional mapping for predicting drug response and enabling personalized medicine -- Future outlook of systems biology.
,
Introduction to systems biology in drug discovery and development -- Methods for in silico biology : model construction and analysis -- Methods in in silico biology : modeling feedback dynamics in pathways -- Simulation of population variability in pharmacokinetics -- Applications of systems biology approaches to target identification and validation in drug discovery -- Lead identification and optimization -- The role of core biological motifs in dose-response modeling : an example with switch-like circuits -- Mechanism based pharmacokinetic-pharmacodynamic modeling during discovery and early development -- Developing oncology drugs using virtual patients of vascular tumor diseases -- Systems modeling applied to candidate biomarker identification -- Simulating clinical trials -- Pathway analysis in drug discovery -- Functional mapping for predicting drug response and enabling personalized medicine -- Future outlook of systems biology.
Weitere Ausg.:
ISBN 9781118016435
Weitere Ausg.:
ISBN 9781118016411
Weitere Ausg.:
ISBN 9781118016428
Sprache:
Englisch
Fachgebiete:
Chemie/Pharmazie
Schlagwort(e):
Arzneimittelentwicklung
;
Arzneimitteldesign
;
In silico-Methode
;
Systembiologie
