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  • 1
    UID:
    gbv_640671063
    Format: VIII + 164 S
    Edition: Online-Ausg. Online-Ressource Karger eBooks Collection 1997-2009
    ISBN: 9783318011340
    Series Statement: Monographs in virology 25
    Content: Viral hepatitis B or C is the most common cause of chronic liver disease worldwide and accounts for about 80% of all hepatocellular carcinoma cases. Thus, combating viral hepatitis remains one of the most pressing public health issues today. Animal models and cell-based systems are essential tools for addressing the many still unresolved basic and clinical problems. Experimental models are needed to better understand the viral life cycles, pathogenetic aspects and natural defense mechanisms, while preclinical models are required for evaluating novel preemptive and therapeutic strategies. This monograph provides a unique synopsis of currently available models of viral hepatitis, highlighting their particular use for basic and translational science. Leading experts discuss new scientific results and evolving methods in various animal and in vitro models, including the woodchuck, duck, mouse, chimpanzee and tupaia, as well as primary hepatocytes and subgenomic HCV replicons.A valuable single source of information, this book will be of interest to all investigators and clinicians working in the fields of viral hepatitis and/or hepatology
    Additional Edition: ISBN 9783318011340
    Additional Edition: ISBN 9783805578097
    Additional Edition: Erscheint auch als Druck-Ausgabe ISBN 9783805578097
    Language: English
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