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    Online Resource
    Online Resource
    Boston, MA : Landes Bioscience and Springer Science+Business Media, LLC
    UID:
    gbv_644978414
    Format: Online-Ressource , v.: digital
    Edition: Online-Ausg. Springer eBook Collection. Biomedical and Life Sciences Electronic reproduction; Available via World Wide Web
    ISBN: 9781441970053
    Series Statement: Advances in Experimental Medicine and Biology 693
    Content: This book aims to bring to the forefront a field that has been developing since the late 1990s called the STAR pathway for Signal Transduction and Activation of RNA. It is a signaling pathway that targets RNA directly, in contrast to the canonical signal-kinase cascade-transcription factor-DNA-RNA. It is proposed to allow quick responses to environment changes such as those necessary in many biological phenomenon such as the nervous system and during development.
    Content: This book aims to bring to the forefront a field that has been developing since the late 1990s called the STAR pathway for Signal Transduction and Activation of RNA. It is a signaling pathway that targets RNA directly; in contrast to the canonical signal - kinase cascade - transcription factor - DNA - RNA. It is proposed to allow quick responses to environment changes such as those necessary in many biological phenomenon such as the nervous system and during development
    Note: Includes bibliographical references and index , Title Page; Copyright Page; DEDICATIONS; PREFACE; ABOUT THE EDITORS...; ABOUT THE EDITORS...; PARTICIPANTS; Table of Contents; CHAPTER 1. STAR TREK AN INTRODUCTION TO STAR FAMILY PROTEINS AND REVIEW OF QUAKING (QKI); CHAPTER 2. THE STAR FAMILY MEMBER QKI AND CELL SIGNALING; CHAPTER 3. INSIGHTS INTO THE STRUCTURAL BASIS OF RNA RECOGNITION BY STAR DOMAIN PROTEINS; CHAPTER 4. POST-TRANSLATIONAL REGULATION OF STAR PROTEINS AND EFFECTS ON THEIR BIOLOGICAL FUNCTIONS; CHAPTER 5. EXPRESSION AND FUNCTIONS OF THE STAR PROTEINS Sam68 AND T-STAR IN MAMMALIAN SPERMATOGENESIS , CHAPTER 6. THE ROLE OF QUAKING IN MAMMALIAN EMBRYONIC DEVELOPMENTCHAPTER 7. DROSOPHILA STAR PROTEINS: WHAT CAN BE LEARNED FROM FLIES?; CHAPTER 8. C. ELEGANS STAR PROTEINS, GLD-1 AND ASD-2, REGULATE SPECIFIC RNA TARGETS TO CONTROL DEVELOPMENT; CHAPTER 9. THE BRANCHPOINT BINDING PROTEIN: IN AND OUT OF THE SPLICEOSOME CYCLE; CHAPTER 10. Reaching for the STARS Linking RNA Binding Proteins to Diseases; INDEX; , STAR trek : an introduction to STAR family proteins and review of QKI / Karen Artzt and Jiang I. Wu -- The STAR family member : quaking (QKI) and cell signaling / Yue Feng and Andrew Bankston -- Insights into the structural basis of RNA : recognition by STAR domain proteins / Sean P. Ryder and Francesca Massi -- Post-translational regulation of STAR proteins and effects on their biological functions / Claudio Sette -- Expression and fuctions of the STAR proteins Sam68 and T-star in mammalian spermatogenesis / Ingrid Ehrmann and David J. Elliott -- The role of quaking in mammalian embryonic development / Monica J. Justice and Karen K. Hirschi -- Drosophila STAR proteins : what can be learned from flies? / Talila Volk -- C. elegans STAR proteins, GLD-1 and ASD-2, regulate specific RNA targets to control development / Min-Ho Lee and Tim Schedl -- The branchpoint binding protein : in and out of the spliceosome cycle / Brian C. Rymond -- Reaching for the STARs : linking RNA binding proteins to diseases / Stephane Richard. , Electronic reproduction; Available via World Wide Web
    Additional Edition: ISBN 9781441970046
    Language: English
    URL: Volltext  (lizenzpflichtig)
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