Umfang:
Online-Ressource (1 online resource (536 p.))
,
digital, PDF file(s).
Ausgabe:
Online-Ausg.
ISBN:
9780511674747
Inhalt:
This major new edition fulfils the need for a single-volume, up-to-date information resource on the etiology, pathogenesis, diagnosis and treatment of diseases of skeletal muscles, including the muscular dystrophies, mitochondrial myopathies, metabolic myopathies, ion channel disorders, and dysimmune myopathies. As background to the clinical coverage, relevant information on advances in molecular and developmental biology, immunopathology, mitochondrial biology, ion-channel dynamics, cell membrane and signal transduction science, and imaging technology is summarized. Combining essential new knowledge with the fundamentals of history-taking and clinical examination, this extensively illustrated book will continue to be the mainstay for practising physicians and biomedical scientists concerned with muscle disease. Regular updates on the clinical and basic science aspects of muscle disease - written mainly by rising stars of myology - will be published on an accompanying website
Inhalt:
The scientific basis of muscle disease -- Structure and function of muscle fibres and motor units -- Myogenic precursor cells -- Biochemical and molecular basis of muscle disease -- Investigation of muscle Disease -- Electrophysiological evaluation of suspected myopathy -- Histopathology and immunoanalysis of muscle -- Ultrastructural study of muscle -- Diagnostic imaging of muscle -- Description of muscle disease: general aspects -- The clinical assessment and a guide to classification of the myopathies -- The principles of molecular therapies for muscle diseases -- Description of muscle disease: specific diseaes -- Dystrophinopathies -- Muscular dystrophies presenting with proximal muscle weakness -- Dystrophies and myopathies of early childhood onset -- Congenital myopathies -- Muscle diseases with prominent muscle contractures -- Facioscapulohumeral muscular dystrophy -- Distal myopathies -- Oculopharyngeal muscular dystrophy -- Myotonic dystrophy -- Mitochondrial myopathies -- Metabolic myopathies -- Muscle ion channelopathies and related disorders -- Inflammatory myopathies -- Autoimmune and inherited disorders of neuromuscular transmission -- Endocrine and toxic myopathies -- Myofibrillar myopathies -- Hereditary inclusion body myopathies -- Other myopathies
Anmerkung:
Title from publisher's bibliographic system (viewed on 05 Oct 2015)
Weitere Ausg.:
ISBN 9780521876292
Weitere Ausg.:
Erscheint auch als Druck-Ausgabe ISBN 978-052-187-629-2
Weitere Ausg.:
Erscheint auch als Druck-Ausgabe ISBN 9780521876292
Sprache:
Englisch
DOI:
10.1017/CBO9780511674747
