Umfang:
Online-Ressource (digital)
ISBN:
9783540788997
Serie:
Advances in Anatomy, Embryology and Cell Biology 200
Inhalt:
Articular cartilage is a unique and highly specialized avascular connective tissue in which the availability of oxygen and glucose is significantly lower than synovial fluid and plasma. Glucose is an essential source of energy during embryonic growth and fetal development and is vital for mesenchymal cell differentiation, chondrogenesis and skeletal morphogenesis. Glucose is an important metabolic fuel for differentiated chondrocytes during post-natal development and in adult articular cartilage and is a common structural precursor for the synthesis of extracellular matrix glycosaminoglycans
Anmerkung:
Includes bibliographical references and index
,
Introduction; Articular Cartilage: Structure, Function, and Pathophysiology; Does Arthritis Have a Nutritional Etiology?; Metabolic Dysfunction in Arthritis; Glucose: An Essential Metabolite and Structural Precursor for Articular Cartilage; Mammalian Sugar Transporter Families: GLUT and SGLT; Molecular Diversity of Facilitative Glucose Transporters in Articular Chondrocytes; Regulation of Glucose Transport by Nonsteroidal Anti-inflammatory Drugs; Glucose Transporters in the Intervertebral Disc; Glucose Transporter Expression and Regulation in Embryonic and Mesenchymal Stem Cells
,
Concluding Remarks
Weitere Ausg.:
ISBN 9783540788980
Weitere Ausg.:
Buchausg. u.d.T. Mobasheri, Ali Facilitative Glucose Transporters in Articular Chondrocytes Berlin : Springer, 2008 ISBN 9783540788980
Weitere Ausg.:
ISBN 3540788980
Sprache:
Englisch
Fachgebiete:
Medizin
Schlagwort(e):
Gelenkknorpel
;
Knorpelzelle
;
Glucosetransport
;
Gelenkknorpel
;
Knorpelzelle
;
Glucosestoffwechsel
DOI:
10.1007/978-3-540-78899-7
