Umfang:
Online-Ressource (VIII, 109 p. 47 illus., 26 illus. in color, online resource)
ISBN:
9783642546686
Serie:
SpringerBriefs in Molecular Science
Inhalt:
This book reviews the latest advances in the development of silicon nano-biotechnology for biological and biomedical applications, which include biosensing, bioimaging, and cancer therapy. In this book, newly developed silicon nano-biotechnology and its biomedical applications are systematically introduced. For instance, fluorescent silicon nanoparticles, serving as novel high-performance biological nanoprobes, are superbly suited to real-time and long-term bioimaging. Silicon nanowire-based sensing platform is especially capable of sensitive, specific, and multiplexed detection of various biological species. Silicon-based nanocarriers with ultra-high drug-loading capacity are highly efficacious for in vitro and in vivo cancer therapies. This book is intended for readers who are interested in the design of functional silicon nanostructures and their biological and biomedical applications. It uses silicon nanoparticles and silicon nanowires as models and discusses topics ranging from their synthesis to their biological applications, the goal being to highlight these exciting achievements as starting points in the field of silicon nano-biotechnology.Yao He is a Professor at Institute of Functional NanoSoft Materials (FUNSOM), Soochow University, China. Yuanyuan Su is an Associate Professor at Institute of Functional NanoSoft Materials (FUNSOM), Soochow University, China.
Anmerkung:
Description based upon print version of record
,
Preface; Contents; 1 Introduction; 1.1…Fabrication of Silicon Nanostructures; 1.2…Biosensor; 1.3…Bioimaging; 1.4…Cancer Therapy; 1.5…Biosafety Assessment; References; 2 Silicon Nanostructures; Abstract; 2.1…Fluorescent Silicon Nanoparticles; 2.2…Silicon Nanowires; 2.2.1 Chemical Vapor Deposition; 2.2.2 Oxide-Assisted Growth; 2.2.3 Metal-Catalyzed Electroless Etching; 2.3…Silicon Nanohybrid; 2.4…Conclusions; References; 3 Silicon-Based Platform for Biosensing Applications; Abstract; 3.1…SiNWs-Based Electrochemical Biosensor; 3.1.1 SiNWs-Based Field-Effect Transistor
,
3.1.1.1 SiNWs-Based FET for Nucleic Acids Detection3.1.1.2 SiNW-FET for Proteins Detection; 3.1.1.3 Other Applications; 3.1.2 Amperometric-Based Biosensors; 3.2…Silicon-Based Optical Biosensor; 3.2.1 Surface-Enhanced Raman Scattering-Based Biosensors; 3.2.2 Fluorescence-Based Biosensors; 3.3…Conclusions and Prospects; References; 4 Silicon-Based Nanoprobes for Bioimaging Applications; Abstract; 4.1…In Vitro Imaging; 4.2…In Vivo Imaging; 4.3…Conclusions and Prospects; References; 5 Silicon-Based Nanoagents for Cancer Therapy; Abstract; 5.1…Chemotherapy; 5.1.1 Drug Delivery
,
5.1.2 Protein and Gene Delivery5.2…Silicon-Based Nanoagents for Phototherapy; 5.2.1 Photodynamic Therapy; 5.2.2 Photothermal Therapy; 5.3…Conclusions and Perspectives; References; 6 Biosafety Assessment of Silicon Nanomaterials; Abstract; 6.1…SiNPs-Related Biosafety Assessment; 6.2…Silicon Nanowires-Related Biosafety Assessment; 6.3…Conclusions; References; 7 Outlook; 7.1…Conclusion; 7.2…Challenges and Perspectives
Weitere Ausg.:
ISBN 9783642546679
Weitere Ausg.:
Erscheint auch als Druck-Ausgabe He, Yao Silicon nano-biotechnology Berlin : Springer, 2014 ISBN 3642546676
Weitere Ausg.:
ISBN 9783642546679
Sprache:
Englisch
Schlagwort(e):
Silicium
;
Nanostruktur
;
Biotechnologie
;
Silicium
;
Nanostruktur
;
Biotechnologie
DOI:
10.1007/978-3-642-54668-6
