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  • 1
    Online Resource
    Online Resource
    Hoboken, N.J. :Wiley,
    UID:
    almafu_9959327679102883
    Format: 1 online resource (xvi, 347 pages, 16 unnumbered pages of plates) : , illustrations (some color)
    ISBN: 9780470423929 , 0470423927 , 9780470423936 , 0470423935
    Content: As research progresses and information continues to proliferate in the field of molecular design for therapeutic use, there is a need for a reference that brings current theory and proven practice together in a how-to volume. This reference guides scientists new to the field on how to design small molecules that interact with critical protein targets. The chapters condense useful material into a manageable format which is carefully organized and presented. It offers an essential resource for a variety of chemists in academia, and the biotech and pharmaceutical industries, as well as profession.
    Note: Drug discoveries by gene family / Karen E. Lackey -- G-protein coupled receptors / Stephen L. Garland and Tom D. Heightman -- Ion channels gene family : strategies for discovering ion channel drugs / Maria L. Garcia and Gregory J. Kaczorowski -- Integrins / David D. Miller -- Strategies for discovering kinase drugs / Jerry L. Adams [and others] -- Protease-directed drug discovery / Richard Sedrani, Ulrich Hommel, and Jor̈g Eder -- Small-molecule inhibitors of protein-protein interactions : challenges and prospects / Adrian Whitty -- Transporters / Anne Hersey, Frank E. Blaney, and Sandeep Modi -- Nuclear receptor drug discovery / Hiroyuki Kagechika and Aya Tanatani -- Summary and comparison of molecules designed to modulate druggable targets in the major gene families / Karen E. Lackey.
    Additional Edition: Print version: Gene family targeted molecular design. Hoboken, N.J. : John Wiley & Sons, ©2009 ISBN 9780470412893
    Additional Edition: ISBN 0470412895
    Language: English
    Keywords: Electronic books. ; Electronic books. ; Electronic books.
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