UID:
almafu_9959329162002883
Format:
1 online resource (lx, 445 pages) :
,
illustrations (some color)
ISBN:
3527312854
,
3527608036
,
9783527608034
,
9783527312856
,
3527607366
,
9783527607365
Content:
This first book to cover neural development, neuronal survival and function on the genetic level outlines promising approaches for novel therapeutic strategies in fighting neurodegenerative disorders, such as Alzheimer's disease. Focusing on transcription factors, the text is clearly divided into three sections devoted to transcriptional control of neural development, brain function and transcriptional dysregulation induced neurological diseases. With a chapter written by Nobel laureate Eric Kandel, this is essential reading for neurobiologists, geneticists, biochemists, cell biologists, neuro.
Note:
Roles of Hes bHLH factors in neural development / Ryoichiro Kageyama, Jun Hatakeyama and Toshiyuiki Ohtsuka -- The role of Pax6 in the nervous system during development and in adulthood : master control regulator or modular function? / Nicole Haubst, Jack Favor, and Magdalena Götz -- Phox2a and Phox2b : essential transcription factors for neuron specification and differentiation / Uwe ERnsberger and Hermann Rohrer -- Functions of LIM-homeodomain proteins in the development of the nervous system / Yangu Zhao, Nasir Malik, and Heiner Westphal -- The roles of serum response factor in brain development and function / Bernd Knöll and Alfred Nordheim -- RE-1 silencing transcription factor (REST) : regulation of neuronal gene expression via modification of the chromatin structure / Gerald Thiel and Mathias Hohl -- Roles of Tlx1 and Tlx3 and neuronal activity in controlling glutamatergic over GABAergic cells fates / Qiufu Ma and Le-ping Cheng -- Transcriptional control of the development of central serotonergic neurons / Zhou-Feng Chen and Yu-Qiang Ding -- Role of Nkx homeodomain factors in the specification and differentiation of motor neurons and oligodendrocytes / Jun Cai and Mengsheng Qiu -- Sox transcription factors in neural development / Michael Wegner and C. Claus Stolt -- The role of CREB and CBP in brain function / Angel Barco and Eric R. Kandel -- CCAAT enhancer binding proteins in the nervous system : their role in development, differentiation, long-term synaptic plasticity, and memory / Cristina M. Alberini -- The role of c-Jun in brain function / Gennadij Raivich and Axel Behrens -- Expression, function, and regulation of transcription factor MEF2 in neurons / Zixu Mao and Xuemin Wang ; -- RORa : an orphan that staggers the mind / Peter M. Gent and Bruce A. Hamilton -- The role of NF-kB in brain function / Barbara Kaltschmidt [and others] --- Calcineurin/NFAT signaling in development and function of the nervous system / Isabella A. Graef, Gerald R. Crabtree, and Fan Wang -- Stimulus-transcription coupling in the nervous system : the zinc finger protein Egr-1 / Oliver G. Rössler ... et al. --The presenilin/g-secretase complex regulates production of transcriptional factors : effects of FAD mutations / Nikolaos K. Robakis and Philippe Marambaud --Transcriptional abnormalities in Huntington's disease / Dimitri Krainc.
Additional Edition:
Print version: Transcription factors in the nervous system. Weinheim : Wiley-VCH, ©2006 ISBN 3527312854
Language:
English
Keywords:
Electronic books.
;
Electronic books.
;
Electronic books.
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/3527608036
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/3527608036
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/3527608036
