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  • 1
    Online Resource
    Online Resource
    Hoboken, NJ :Wiley-Blackwell,
    UID:
    edocfu_9959327489702883
    Format: 1 online resource
    ISBN: 9781119166184 , 1119166187 , 9781119166177 , 1119166179 , 9781119166191 , 1119166195
    Content: "Provide the insights of bio-pigmentation and molecular mechanisms of microbial biosynthesis of pigments. The new avenues of bio-pigments as sustainable resources to overcome from chemically synthesized pigments under safety net will be established"--Provided by publisher.
    Note: Machine generated contents note: Section 1: Introduction of variety of microorganisms and their ability for color production. Section 2: Overview of the methodologies applied to screen and identify the variety of color producing microorganisms. Section 3: Biochemistry and molecular mechanisms of color producing microorganisms among diverse microbial population. Section 4: Systems biology based metabolic engineering of bio-pigments in microorganisms. Section 5: The regulations, challenges and implications of enforcements from regulatory agencies. , List of Contributors xv; ; Introduction xvii; ; 1 INTRODUCTION OF NATURAL PIGMENTS FROM MICROORGANISMS 1 ; Siyuan Wang, Fuchao Xu, and Jixun Zhan ; ; 1.1 Introduction 1; ; 1.2 Microbial Pigments from Eukaryotic Sources 2; ; 1.2.1 Pigments from Algae 2; ; 1.2.2 Pigments from Fungi 4; ; 1.2.3 Pigments from Yeasts 7; ; 1.3 Natural Pigments from Prokaryotes 9; ; 1.3.1 Natural Pigments from Cyanobacteria 9; ; 1.3.2 Natural Pigments from Bacteria 10; ; 1.4 Conclusion 16; ; References 16; ; 2 ESTABLISHING NOVEL CELL FACTORIES PRODUCING NATURAL PIGMENTS IN EUROPE 23 ; Gerit Tolborg, Thomas Isbrandt, Thomas Ostenfeld Larsen, , And Mhairi Workman ; ; 2.1 Introduction 23; ; 2.2 Colorants 25; ; 2.2.1 Classification of Colorants 25; ; 2.2.2 Monascus Pigments 26; ; 2.2.3 Biosynthesis of Monascus Pigments 29; ; 2.2.4 Derivatives of Monascus Pigments 31; ; 2.3 Screening for Monascus Pigment-Producing Cell Factories for the European Market 32; ; 2.3.1 Cell Factory Selection and Identification 32; ; 2.3.2 From Single Pigment Producers to High-Performance Cell Factories 33; ; 2.4 Assessment of the Color Yield 34; ; 2.4.1 Pigment Purification and Quantification 34; ; 2.4.2 Detection and Identification 37; ; 2.4.3 Quantification 38; ; 2.4.4 CIELAB 41; ; 2.5 Optimizing Cellular Performance: Growth and Pigment Production 41; ; 2.5.1 Assessment of Classical Physiological Parameters 42; ; 2.5.2 Media Composition 42; ; 2.5.3 Cultivation Parameters 44; ; 2.5.4 Type. , Of Cultivation 46; ; 2.5.5 Metabolic Engineering 48; ; 2.6 Pigment Properties 50; ; 2.7 Conclusion 51; ; References 51; ; 3 COLOR-PRODUCING EXTREMOPHILES 61 ; Eva García-López, Alberto Alcazar, Ana Maria Moreno, , And Cristina Cid ; ; 3.1 Introduction 61; ; 3.2 Color-Producing Extremophiles 62; ; 3.2.1 Thermophiles and Hyperthermophiles 63; ; 3.2.2 Psychrophiles and Psychrotolerants 63; ; 3.2.3 Alkaliphiles 66; ; 3.2.4 Acidophiles 66; ; 3.2.5 Piezophiles and Piezotolerants 66; ; 3.2.6 Halophiles and Halotolerants 67; ; 3.2.7 Radiophiles 67; ; 3.3 Microbial Pigments 68; ; 3.3.1 Chlorophylls and Bacteriochlorophylls 68; ; 3.3.2 Carotenoids and Phycobilins 69; ; 3.3.3 Violacein 70; ; 3.3.4 Prodigiosin 70; ; 3.3.5 Pyocyanin 70; ; 3.3.6 Azaphilones 70; ; 3.3.7 Bacteriorhodopsin 71; ; 3.3.8 Cytochromes 71; ; 3.3.9 Other 72; ; 3.4 Biotechnological Applications of Microbial Pigments from Extremophiles 73; ; 3.4.1 Applications in the Food Industry 74; ; 3.4.2 Applications in the Pharmaceutical Industry 77; ; 3.4.3. , Dendrorhous, Formerly Phaffia rhodozyma 94; ; 4.4.2 Agrobacterium aurantiacum and Other Bacteria 95; ; 4.4.3 Advantages over Other Carotenoids 95; ; 4.4.4 Astaxanthin for Salmon and Trout Feeds 96; ; 4.4.5 Astaxanthin for Humans 97; ; 4.5 Zeaxanthin 97; ; 4.6 Canthaxanthin 98; ; 4.7 Torulene and Thorularhodin 99; ; 4.8 Prospects for Carotenoid Production by Genetically Modified Microorganisms 99; ; 4.8.1 Escherichia coli and Other Hosts 99; ; 4.8.2 Directed Evolution and Combinatorial Biosynthesis 101; ; 4.9 Conclusion 102; ; References 104; ; 5 C50 CAROTENOIDS: OCCURRENCE, BIOSYNTHESIS, GLYCOSYLATION, AND METABOLIC ENGINEERING FOR THEIR OVERPRODUCTION 107 ; Sabine A.E. Heider, Nadja A. Henke, Petra Peters-Wendisch, and Volker F. , Wendisch ; ; 5.1 Introduction 107; ; 5.2 Occurrence and Biological Function of C50 Carotenoids 108; ; 5.3 Biosynthesis of C50 Carotenoids 110; ; 5.4 Glycosylation of C50 Carotenoids 114; ; 5.5 Overproduction of C50 Carotenoids by Metabolic Engineering 115; ; 5.6 Conclusion 118; ; Acknowledgments 119; ; References 119; ; 6 BIOPIGMENTS AND MICROBIAL BIOSYNTHESIS OF -CAROTENOIDS 127 ; Rosemary C. Nwabuogu, Jennifer Lau, and Om V. , MECHANISMS OF MONASCUS PIGMENTS 173 ; Changlu Wang, Di Chen, , And Jiancheng Qi ; ; 8.1 Introduction 173; ; 8.2 Monascus Pigments 174; ; 8.3 The Properties of Monascus Pigments 176; ; 8.3.1 Solubility 176; ; 8.3.2 Stability 177; ; 8.3.3 Safety 177; ; 8.4 Functional Properties of Monascus Pigments 177; ; 8.4.1 Antimicrobial Activities 178; ; 8.4.2 Anti-inflammatory Activities 178; ; 8.4.3 Anti-obesity Activities 178; ; 8.4.4 Anticancer Activities 178; ; 8.5 Biosynthetic Pathway of Monascus Pigments 179; ; 8.6 Biosynthetic Pathway of Related Genes 181; ; 8.7 Factors Affecting Monascus Pigment Production 184; ; 8.7.1 Solid-State Fermentation 185; ; 8.7.2 Submerged Fermentation 186; ; 8.7.3 Carbon Source 186; ; 8.7.4 Nitrogen Source 187; ; 8.7.5 Temperature 187; ; 8.7.6 Light 187; ; Referencess 187; ; 9 DIVERSITY AND APPLICATIONS OF VERSATILE PIGMENTS PRODUCED BY MONASCUS. , SP 193 ; Sunil H. Koli, Rahul K. Suryawanshi, Bipinchandra K. Salunke, and Satish V. Patil ; ; 9.1 Introduction 193; ; 9.2 Pigment-Producing Monascus Strains 195; ; 9.3 Various Types of Monascus Pigments 199; ; 9.4 Extraction and Purification of Monascus Pigments 203; ; 9.5 Detection and Purification 204; ; 9.5.1 UV-Vis Spectrophotometric Methods 204; ; 9.5.2 Column Chromatography 204; ; 9.5.3 Thin-Layer Chromatography 205; ; 9.5.4 High-Performance Liquid Chromatography 205; ; 9.6 Applic.
    Additional Edition: Print version: Bio-pigmentation and biotechnological implementations. Hoboken, NJ : Wiley-Blackwell, 2017 ISBN 9781119166146
    Language: English
    Keywords: Electronic books.
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