Format:
1 Online-Ressource (xii, 175 Seiten, 24612 KB)
,
Illustrationen, Diagramme
Content:
Proteins are natural polypeptides produced by cells; they can be found in both animals and plants, and possess a variety of functions. One of these functions is to provide structural support to the surrounding cells and tissues. For example, collagen (which is found in skin, cartilage, tendons and bones) and keratin (which is found in hair and nails) are structural proteins. When a tissue is damaged, however, the supporting matrix formed by structural proteins cannot always spontaneously regenerate. Tailor-made synthetic polypeptides can be used to help heal and restore tissue formation. Synthetic polypeptides are typically synthesized by the so-called ring opening polymerization (ROP) of α-amino acid N-carboxyanhydrides (NCA). Such synthetic polypeptides are generally non-sequence-controlled and thus less complex than proteins. As such, synthetic polypeptides are rarely as efficient as proteins in their ability to self-assemble and form hierarchical or structural supramolecular assemblies in water, and thus, often require…
Note:
Dissertation Universität Potsdam, Mathematisch-Naturwissenschaftliche Fakultät 2017
Additional Edition:
Erscheint auch als Druck-Ausgabe Vacogne, Charlotte New synthetic routes towards well-defined polypeptides, morphologies and hydrogels Potsdam, 2016
Language:
English
Keywords:
Polypeptide
;
Copolymere
;
Glutamate
;
Aminopentensäurederivate
;
Ringöffnungspolymerisation
;
Carbonsäurederivate
;
Hochschulschrift
URN:
urn:nbn:de:kobv:517-opus4-396366
URL:
https://nbn-resolving.org/urn:nbn:de:kobv:517-opus4-396366
URL:
https://d-nb.info/1219077704/34
Author information:
Schlaad, Helmut 1967-
