UID:
almafu_9958058263002883
Umfang:
viii, 311 p. :
,
ill.
ISBN:
9783318011654
,
3318011657
Serie:
Current directions in autoimmunity ; v. 8
Inhalt:
The understanding of B cell biology has increased and expanded enormously in the last three decades. It is now known that B cells, in addition to just differentiating into antibody-secreting cells, serve many other vital functions. For example, their roles as antigen-presenting cells and cytokine-producing cells as well as effector cells and regulatory cells are well appreciated now. Indeed, the pathologic role of B cells in many autoimmune disorders may be largely autoantibody-independent. Today, the B cell is of considerable interest not only to immunologists but also to mainstream clinicians and scientists. The current volume covers the latest information on the functions of B cells in normal and disease states, and their therapeutic antagonism. Chapters cover cutting-edge topics from the basic to the clinical, including B cells in infection and autoimmunity, CD19-CD21 signal transduction complex, marginal zone B cell physiology and disease, B cell growth and differentiation, their role in rheumatoid arthritis, SLE treatment, the BAFF/APRIL system and B lymphocyte malignancies. This book is recommended reading for cellular and molecular immunologists as well as for rheumatologists, hematologists and clinical immunologists, and all those interested in human diseases in which B cells play an important contributory role.
Anmerkung:
Bibliographic Level Mode of Issuance: Monograph
,
Determinations of B cell fate in immunity and autoimmunity / Noelle, R.J.; Erickson, L.D. -- Regulatory roles for cytokine-producing B cells in infection and autoimmune disease / Lund, F.E. ... [et al.] -- The CD19-CD21 signal transduction complex of B lymphocytes regulates the balance between health and autoimmune disease / Tedder, T.F. ... [et al.] -- Marginal zone B cell physiology and disease / Lopes-Carvalho, T.; Kearney, J.F. -- Dendritic cells control B cell growth and differentiation / Jego, G. ... [et al. ] -- The biology of CD20 and its potential as a target for mAb therapy / Cragg, M.S. ... [et al.] -- B lymphocyte depletion in rheumatoid arthritis / Edwards, J.C.W.; Leandro, M.J.; Cambridge, G. -- Treatment of SLE with anti-CD20 monoclonal antibody / Looney, R.J.; Anolik, J.; Sanz, I. -- The biochemistry and biology of BAFF, APRIL and their receptors / Kalled, S.L.; Ambrose, C.; Hsu, Y.-M. -- The BAFF/APRIL system / Mackay, F. ... [et al.] -- Human B lymphocyte malignancies / Jelinek, D.F.; Darce, J.R. -- BlySfulness does not equal blissfulness in systemic lupus erythematosus / Stohl, W.
,
English
Weitere Ausg.:
ISBN 9783805578516
Weitere Ausg.:
ISBN 3805578512
Sprache:
Englisch
Fachgebiete:
Medizin
Schlagwort(e):
Aufsatzsammlung
;
Aufsatzsammlung
;
Aufsatzsammlung
;
Aufsatzsammlung
