UID:
almafu_9958354957002883
Umfang:
1 online resource (994p.)
ISBN:
9783110852455
Anmerkung:
Frontmatter --
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Preface --
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Contents --
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1. Fritz Lipmann (1899-1986) --
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1. Fritz Lipmann (1899-1986) --
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Life with Fritz --
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A Long Life in Times of Great Upheaval --
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Fritz Lipmann: In Memoriam --
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Lipmann's Remarkably Fulfilled Life as a Researcher --
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Fritz Lipmann: June 12, 1899 - July 24, 1986 --
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Fritz Lipmann Molding the Design of Molecular Bioenergetics --
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Recollections of Fritz Lipmann, 1941-1945 --
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In Celebration of the Scientific Genius of Fritz Lipmann --
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Lipmann and "Not Strictly Biochemistry" --
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Communication in Metabolic Control Intuition and Method in Biochemistry: Four Years each with Krebs and Lipmann --
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Fritz Lipmann: Squiggle to Protein Sulfation --
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Fritz Lipmann (1899-1986), Honorary Member of the Leopoldina Academy --
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Dahlem in the Late Nineteen Twenties --
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Our Apprenticeship --
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The Kaiser-Wilhelm-Institutes in Berlin-Dahlem in the Late 1930ies and Early 1940ies: Reminiscences of a Student of Biochemistry --
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On the Origin of the Squiggle (~) --
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2. Biochemistry Comes of Age --
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2. Biochemistry Comes of Age --
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The History of Metabolites Isolated from Urine --
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The Pentose Phosphate Pathway --
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Glycolysis and the Dawn of Modern Biochemistry --
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Energy-Rich Bonds and Enzymatic Peptide Synthesis --
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A Nostalgic View of the TCA Cycle in Bacteria --
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The Role of Vitamins and their Carrier Proteins in Citrate Fermentation --
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Lipmann's Influence on Firefly Luminescence --
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Sulfur in Biomimetic Peptide Syntheses --
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The Function of Teichoic Acids in Walls and Membranes of Bacteria --
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The Amidotransferases: Origins of the Concept of Affinity Labeling of Enzymes --
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Intracellular Protein Degradation: Past, Present and Future --
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Lipmann's Squiggle and the Unification of Cellular Structure and Function --
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The Historical Intermingling of Biochemistry and Cell Biology --
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Regulation of Function of Membrane Proteins by Phosphorylation and Dephosphorylation --
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Molecular Biology of Brain Peptides and their Cognate Receptors --
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The Biological Activity of Tuftsin, Thr-Lys-Pro-Arg --
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Biosynthesis of Linear Gramicidin, Pentadeca Peptide, is Tight Linked to Serine Metabolism and to Membranous Phosphoglyceride --
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From Phosphoenolpyruvate Carboxykinase to Sporulation: Personal Reflections on Dr. F. Lipmann --
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Research on Nonribosomal Systems: Biosynthesis of Peptide Antibiotics --
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Metabolism of Carnosine and Related Peptides --
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3. Molecular Biology Sharpens its Tools --
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3. Molecular Biology Sharpens its Tools --
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DNA Repair in Human Cells: Molecular Cloning of cDNAS Coding for Enzymes Related to Repair --
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Acyl ~ Phosphate Intermediates in Oxidative DNA Sugar Damage by Antibiotics --
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Rts1: A Multiphenotypic, Unusual Temperature Sensitive Drug Resistance Factor --
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The Partial Dependency of Human Prostatic Growth Factor on Steroid Hormones in Stimulating Thymidine Incorporation into DNA --
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Developmentally Regulated Gene Amplification in Rhynchosciara --
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Fritz Lipmann, a Few Personal Memories, and: What Else Came Out of the High-Energy Phosphate Bond? --
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Regulation of Gene Expression by Posttranslational Modification of Transcription Factors --
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How Does the Arginine Repressor Regulate the Synthesis of Arginine Biosynthetic Enzymes? --
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The Biochemistry and Molecular Biology of the Terminal Reactions of Methionine Biosynthesis in Escherichia coli --
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The Wheat Embryo, Then and Now --
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Mechanism of Cytotoxic Action and Structures of Thiadiazolo-pyrimidines --
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Architecture of Ribosomal Particles as Investigated by Image Reconstruction and X-Ray Crystallographic Studies --
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Initiation of Protein Synthesis: Early Participation and Recent Revisit --
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Structure of Ribosomal RNA Genes of Eukaryotes: Some Solved and Unsolved Questions --
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Energetics and Dynamics of the Protein- Synthesizing Machinery --
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Expression --
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Punctuation in the Genetic Code: A Plausible Basis for the Degeneracy of the Code to Initiate Translation --
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Reconstruction of Translation: Role of EF-P in Regulation of Peptide Bond Formation --
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On the Role of Spermine in Protein Synthesis --
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4. Functional Dynamics --
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4.1 The Squiggle - Symbol of Bioenergetics --
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4.1 The Squiggle - Symbol of Bioenergetics --
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Energy-Rich Compounds and Work --
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Squiggle Phosphate of Inorganic Pyrophosphate and Polyphosphates --
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Enzymology of 3'-Squiggled Nucleotides --
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Pyridine Nucleotides as Group Transfering Coenzymes --
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The Nature of Squiggle in Oxidative Phosphorylation --
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Motional Dynamics of Fatty Acids: Advantages of 15N and Deuterium Substituted Fatty Acid Spin Labels for Studies of Lipid-Protein Interactions and Motion in Membrane Bilayers --
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Thyroid Hormones and Oxidative Phosphorylation --
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Structure-Activity Relationships of Natural and Synthetic E-β-Methoxyacrylates of the Strobilurin and Oudemansin Series --
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The Intracellular Mechanism of Insulin Action --
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Unity and Diversity in Biological Redox Catalysis: Comparative Enzymology of Some Microbial Oxidoreductases Showing Variation in Cofactor Identity --
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Ammonia-Forming, Dissimilatory Nitrite Reductases as a Homologous Group of Hexaheme C-Type Cytochromes in Metabolically Diverse Bacteria --
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Halorhodopsin --
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Control of Futile Transmembrane Potassium Cycling in Escherichia coli --
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Bioenergetics of Protein Transport into Mitochondria: Role of ΔΨ and of Nucleoside Triphosphates --
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Some Recent Functional and Structural Contributions to the Molecular Mechanism of Photosynthesis --
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Salt Toxicity and Mineral Deficiency in Plants: Cytoplasmic Ion Homeostasis, a Necessity for Growth and Survival under Stress --
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4.2 Molecular Recognition and Communication --
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4.2 Molecular Recognition and Communication --
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Dawn of Ca Research: Regulation of Muscle Contraction --
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Comparative Aspects of the Mechanisms of Energy Transduction in Sarcoplasmic Reticulum between Rabbit and Frog Skeletal Muscle --
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Caltrin: A Versatile Regulator of Calcium Transport in Spermatozoa --
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Protein Kinase C, the Structural Heterogeneity and Differential Expression in Rat Brain --
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Regulation of Erythrocyte Membrane Cytoskeletal Protein Interactions by Phosphorylation --
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A Kinase Splitting Membranal Proteinase: Use in the Study of Receptors Involved in the Cellular Response to Hormones --
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Fritz Lipmann, Phosphoproteins and Regulation of Aromatic Amino Acid Hydroxylase Activity --
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The Regulation of Hepatic Phenylalanine Hydroxylase by Phosphorylation- Dephosphorylation --
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Catabolite Inactivation and Adenylate Cyclase in Yeast --
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Protein Modification by Tyrosine-Sulfation: Possible Functional Implications --
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Proteoglycans and Connective Tissue Pathobiochemistry --
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Acylation of Myelin Proteolipid Protein: A Link to the Past --
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The Unusual Regulation of the Adenylyl cyclase of Amphibian Oocytes by Progesterone - A Review --
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Sterol Synergism, a Tool for Studies on Sterol Function --
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Chemical Modification of Benzodiazepine Receptors of Cortical P2 Membranes --
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Dual Pathways for the Catabolism of γ- Hydroxybutyrate: Cytosolic and Mitochondrial Mechanisms --
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5. Evolution --
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5. Evolution --
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Prebiotic Syntheses and the Mechanism of Early Chemical Evolution --
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Prebiotic Roots of Informed Protein Synthesis: Nature of the Lipmann Connection --
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A Case for an Additional RNA Base Pair in Early Evolution --
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Inorganic Pyrophosphate in Cellular Energetics and Evolution --
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Selforganization in Biosystems --
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List of Contributors --
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Acknowledgements --
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Lipmann's Coworkers at Massachusetts General Hospital, Boston, and the Rockefeller University, New York --
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Fritz Lipmann: Bibliography 1924-1985 --
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Index
Weitere Ausg.:
ISBN 978-3-11-011585-7
Sprache:
Englisch
DOI:
10.1515/9783110852455
URL:
https://doi.org/10.1515/9783110852455
URL:
https://doi.org/10.1515/9783110852455