UID:
almafu_9959327759602883
Format:
1 online resource (x, 290 pages) :
,
illustrations
ISBN:
0470093749
,
9780470093740
,
0470093730
,
9780470093733
,
0470093765
,
9780470093764
,
128027638X
,
9781280276385
Series Statement:
Novartis Foundation symposium ; 264
Content:
This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a better understanding of the cellular and molecular basis of these diseases. Topics include:How nuclear structure and location within a nucleus affect gene expressionChromatin organization and cell differentiationThe nature of the interactions between the nuclear envelope and the cytoskeletonThe extent to which the cytoskeleton mediates communication between the cell membrane and nucleus in regulating gene expression and whether disruption of such.
Note:
Proceedings of the Novartis Foundation Symposium on Nuclear Organization in Development and Disease, held at Novartis Foundation, London, Jan. 27-29, 2004.
,
Editors: Derek J. Chadwick, Jamie Goode.
,
Nuclear lamins: building blocks of nuclear structure and function / Robert D. Goldman, Anne E. Goldman and Dale K. Shumaker -- Aspects of nuclear envelope dynamics in mitotic cells / Brian Burke, Catherine Shanahan, Davide Salina and Melissa Crisp -- Components of the nuclear envelope and their role in human disease / Howard J. Worman -- Nuclear membrane protein emerin: roles in gene regulation, actin dynamcs and human disease / Katherine L. Wilson, James M. Holaska, Rocio Montes de Oca, Kathryn Tifft, Michael Zastrow, Miriam Segura-Totten, Malini Mansharamani and Luiza Bengtsson -- Identification of novel integral membrane proteins of the nuclear envelope with potential disease links using subtracttive proteomics / Eric C. Schirmer, Laurence Florens, Tinglu Guan, John R. Yates III and Larry Gerace -- Genetics of laminopathies / Rabah Ben Yaou, Antoine Muchir, Takuro Arimura, Catherine Massart, Laurnce Demay, Pascale Richard and Gisele Bonne -- Muscular dystrophies related to the cytoskeleton/nuclear envelope / Kristen Nowak, Karl McCullagh, Ellen Poon and Kay E. Davies -- Skeletal and cardiac muscle defects in a murine model of Emery-Dreifuss muscular dystrophy / M.J. Grattan, C. Kondo, J. Thurston, P. Alakija, B.J. Burke, C. Stewart, D. Syme and W.R. Giles -- Mutiple pathways tether telomeres and silent chromatin at the nuclear periphery: functional implications for Sir-mediated repression / Angela Taddei, Marc R. Gartenbrg, Frank R. Neumann, Florence Hediger and Susan M. Gasser -- A-type lamin-linked lipodystrophies / Corinne Vigouroux and Jacqueline Capeau -- Cytosckeletal defects in amyotrophic lateral sclerosis (motor neuron disease) / Jean-Pierre Julien, Stephanie Millecamps and Jasna Kriz -- LMNA mutations in progeroid syndromes / Shurong Huang, Brian K. Kennedy and Junko Oshima -- A genetic approach to study the role of nuclear envelope components in nuclear positioning / Daniel A. Starr and Min Han -- A lamin-dependent pathway that regulates nuclear organization, cell-cycle progression and germ-cell development / Ayelet Margalit, Jun Liu, Alexandra Fridkin, Katherine L. Wilson and Yosef Gruenbaum -- Mutations in the mouse Lmma gene causing progeria, muscular dystrophy and cardiomyopathy / Serguei Kozlov, Leslie Mounkes, Dedra Cutler, Terry Sullivan, Lidia Hernandez, Nicolas Levy, Jeff Rottman and Colin L. Stewart -- The nuclear membrane and mechanotransduction: impaired nuclear mechanics and mechanotransduction in lamin A/C-deficient cells / Jan Lammerding and Richard T. Lee.
Additional Edition:
Print version: Chadwick, Derek. Nuclear organization in development and disease. Hoboken, NJ : Wiley, 2005 ISBN 0470093730
Language:
English
Keywords:
Electronic books.
;
Conference papers and proceedings.
;
Electronic books.
;
Conference papers and proceedings.
;
Electronic books.
;
Conference papers and proceedings.
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/0470093765
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/0470093765
URL:
https://onlinelibrary.wiley.com/doi/book/10.1002/0470093765
