Kooperativer Bibliotheksverbund

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Format: 1 online resource , illustrations (black and white)

ISBN: 9781000173574 , 1000173577 , 9780429296611 , 0429296614 , 9781000173611 , 1000173615 , 9781000173659 , 1000173658

Content: The first volume of the "Handbook of Polyhydroxyalkanoates (PHA): Microbial Biosynthesis and Feedstocks" focusses on feedstock aspects, enzymology, metabolism and genetic engineering of PHA biosynthesis. It addresses better understanding the mechanisms of PHA biosynthesis in scientific terms and profiting from this understanding in order to enhance PHA biosynthesis in bio-technological terms and in terms of PHA microstructure. It further discusses making PHA competitive for outperforming established petrol-based plastics on industrial scale and obstacles for market penetration of PHA. Aimed at professionals and graduate students in Polymer (plastic) industry, wastewater treatment plants, food industry, biodiesel industry, this book Covers the intracellular on-goings in PHA-accumulating bacteria Assesses diverse feedstocks to be used as carbon source for PHA production including current knowledge on PHA biosynthesis starting from inexpensive waste feedstocks Summarizes recent relevant results dealing with PHA production from various organic by-products Presents the key elements to understand and fine-tune the microstructure and sequence-controlled molecular architecture of PHA co-polyesters Discusses the use of CO-rich syngas, sourced from various organic waste materials, for PHA biosynthesis

Note: 〈P〉Chapter 1: Monomer-Supplying Enzymes for Polyhydroxyalkanoate Biosynthesis〈BR〉1.1 Introduction〈BR〉1.2 PHA Biosynthesis Pathways and Related Enzymes〈BR〉1.3 Monomer-Supplying Enzymes〈BR〉1.4 Monomer-Supplying Pathways and Enzymes Involved〈BR〉1.5 Conclusions and Outlook〈BR〉 References〈/P〉〈P〉Chapter 2: PHA Granule-Associated Proteins and their Diverse Functions〈BR〉2.1 Introduction〈BR〉2.2 Granule Assembly Models〈BR〉2.3 GAPs with Enzymatic Activity: PHA Synthases and Depolymerases〈BR〉2.4 Non-Enzymatic GAPs: Transcriptional Regulators and Phasins〈BR〉2.5 Functional Diversity of Phasins〈BR〉2.6 What Makes a Phasin a Phasin?〈BR〉2.7 Biotechnological Applications of GAPs〈BR〉2.8 Conclusions and Outlook〈BR〉 References〈/P〉〈P〉Chapter 3: Genomics of PHA Synthesizing Bacteria〈BR〉3.1 Introduction〈BR〉3.2 Short-Chain-Length PHA (scl-PHA) Producing Bacteria〈BR〉3.3 Medium-Chain-Length PHA (mcl-PHA) Producing Bacteria〈BR〉3.4 Scl-co-mcl-Copolymer Producers〈BR〉3.5 Genomics of mcl-PHA Producing Bacteria〈BR〉3.6 The Genomics of mcl-PHA Metabolism〈BR〉3.7 Mcl-PHA Synthesis from Vegetable Oils and Fats〈BR〉3.8 Genome Analysis of Halomonas Species〈BR〉3.9 Genome Analysis of Paracoccus Species〈BR〉3.10 The PHA Production Machinery in Pseudomonas putida, Cupriavidus necator, Halomonas spp. and Paracoccus spp.〈BR〉3.11 Domain Organization and Structural Comparison of PhaC from Cupriavidus necator, Halomonas lutea and Paracoccus denitrificans〈BR〉 References〈/P〉〈P〉Chapter 4: Molecular Basis of Medium-Chain Length-PHA Metabolism of Pseudomonas putida〈BR〉4.1 Pseudomonas putida, a Model Bacterium for the Production of Medium-Chain-Length PHA〈BR〉4.2 The PHA Cycle and its Key Proteins〈BR〉4.3 Metabolic Pathways Involved in mcl-PHA Production in P. putida〈BR〉4.4 PHA Metabolism Regulation〈BR〉4.5 Conclusions and Outlook〈BR〉 References〈/P〉〈P〉Chapter 5: Production of Polyhydroxyalkanoates by Paraburkholderia and Burkholderia species: A Journey from the Genes through Metabolic Routes to their Biotechnological Applications〈BR〉5.1 Introduction〈BR〉5.2 PHA Synthases〈BR〉5.3 Genomic Analysis of pha Genes on Paraburkholderia and Burkholderia Species〈BR〉5.4 Metabolic Routes of PHA Synthesis〈BR〉5.5 PHA Production from Low-Cost Substrates〈BR〉5.6 Properties of PHA Synthesized by Paraburkholderia and Burkholderia Species〈BR〉5.7 Biomedical and Biotechnological Applications〈BR〉 References〈/P〉〈P〉Chapter 6: Genetic Engineering as a Tool for Enhanced PHA Biosynthesis from Inexpensive Substrates〈BR〉6.1 Introduction〈BR〉6.2 Engineering Techniques Applied to Obtain Recombinant Strains for PHA Production〈BR〉6.3 The Use of Whey as Carbon Source〈BR〉6.4 The Use of Molasses as Carbon Source〈BR〉6.5 The Use of Lipids as Carbon Source〈BR〉6.6 The Use of Starchy Materials as Carbon Source〈BR〉6.7 The Use of Lignocellulosic Materials as Carbon Source〈BR〉6.8 Conclusions and Outlook〈BR〉 References〈/P〉〈P〉Chapter 7: Biosynthesis and Sequence Control of scl-PHA and mcl-PHA〈BR〉7.1 Introduction〈BR〉7.2 The Key Factors of PHA Biosynthesis〈BR〉7.3 Sequence Control of scl-PHA and mcl-PHA〈BR〉 References〈/P〉〈P〉〈BR〉Chapters 8-15: Feedstocks〈/P〉〈P〉Chapter 8: Inexpensive and Waste Raw Materials for PHA Production〈BR〉8.1 Introduction〈BR〉8.2 Oleaginous lipid-based feedstocks〈BR〉8.3 Mixed Organic Acid Feedstocks〈BR〉8.4 Mono- and Polysaccharide Feedstocks〈BR〉8.5 Carbon Dioxide as a Feedstock〈BR〉8.6 Other Carbon Feedstocks〈BR〉8.7 Conclusions and Outlook〈BR〉 References〈/P〉〈P〉Chapter 9: Sustainable Production of Polyhydroxyalkanoates from Crude Glycerol〈BR〉9.1 Introduction -- Polyhydroxyalkanoates (PHA)〈BR〉9.2 Crude Glycerol from Biodiesel Manufacture〈BR〉9.3 Metabolic Pathways of PHA Synthesis from Glycerol〈BR〉9.4 Production of PHA from Crude Glycerol〈BR〉9.5 Characterization of PHA Synthesized from Glycerol〈BR〉9.6 Metabolic Engineering for Glycerol-Based PHA Production〈BR〉9.7 Impact of Crude Glycerol on the Molecular Mass of PHA〈BR〉9.8 Conclusions and Outlook〈BR〉 References〈/P〉〈P〉Chapter 10: Biosynthesis of Polyhydroxyalkanoates (PHA) from Vegetable Oils and its By-products by Wild-Type and Recombinant Microbes〈BR〉10.1 Introduction〈BR〉10.2 Biosynthesis of PHA from Plant Oils〈BR〉10.3 Challenges in Using Different Types of Microorganisms in Large Scale PHA Production〈BR〉10.4 Application of Waste Vegetable Oils and Non-Food Grade Plant Oils for Large Scale Production of PHA〈BR〉10.5 Conclusions and Outlook〈BR〉 References〈/P〉〈P〉Chapter 11: Production and Modification of PHA Polymers Produced from Long-Chain Fatty Acid〈BR〉11.1 Introduction〈BR〉11.2 Strategies for Production of mcl-PHA〈BR〉11.3 Strategies for Maximum Volumetric Productivity〈BR〉11.4 Strategies for Improved Substrate Yields from MCFAs and LCFAs〈BR〉11.5 Extracellular Lipase for Triacylglyceride Consumption〈BR〉11.6 Biosynthesis and Monomer Composition〈BR〉11.7 Functional Modifications of mcl-PHA〈BR〉11.8 Cross-Linking〈BR〉11.9 Conclusions and Outlook〈BR〉 References〈/P〉〈P〉Chapter 12: Converting Petrochemical Plastic to Biodegradable Plastic〈BR〉12.1 Introduction: The Plastic Waste Issue〈BR〉12.2 Strategies for Up-Cycling of Plastic Waste〈BR〉12.3 Enzymatic Degradation of Petrochemical Plastics〈BR〉12.4 Metabolism of Plastics' Monomers and the Connection with PHA〈BR〉12.5 Conclusions and Outlook〈BR〉 References〈/P〉〈P〉Chapter 13: Comparing Heterotrophic with Phototrophic PHA Production -- Concurring or Complementing Strategies?〈BR〉13.1 Introduction -- The Status Quo of PHB Production〈BR〉13.2 Heterotrophic PHA Production for Comparison〈BR〉13.3 PHB Synthesis in Cyanobacteria〈BR〉13.4 Light as Energy Source for Cyanobacteria〈BR〉13.5 CO2 as a Carbon Source for Cyanobacteria〈BR〉13.6 Nutrients for Cyanobacterial Growth〈BR〉13.7 Other Growth Conditions for Cyanobacteria〈BR〉13.8 Current Status of Phototrophic PHA Production〈BR〉13.9 Phototrophic Cultivation Systems〈BR〉13.10 Recombinant Cyanobacteria for PHA Production〈BR〉13.11 PHA Isolation from the Cells, Purification and Resulting Qualities〈BR〉13.12 Utilisation of Residual Cyanobacteria Biomass〈BR〉13.13 Comparing Heterotrophically with Phototrophically Produced PHB〈BR〉13.14 Conclusions and Outlook〈BR〉 References〈/P〉〈P〉Chapter 14: Coupling Biogas (CH4) with PHA Biosynthesis〈BR〉14.1 Introduction〈BR〉14.2 Biogas Market〈BR〉14.3 Methanotrophs〈BR〉14.4 PHA Biosynthesis from Methane〈BR〉14.5 Genome Scale Metabolic Models as a Tool for Understanding the Metabolism of PHB in Methanotrophs〈BR〉14.6 Bioreactors for Biogas Bioconversion〈BR〉14.7 Techno-Economic Analysis of PHA Production from Biogas〈BR〉 References〈/P〉〈P〉Chapter 15: Syngas as a Sustainable Carbon Source for PHA Production〈BR〉15.1 Introduction〈BR〉15.2 Syngas〈BR〉15.3 Production of Syngas from Organic Waste and Biomass〈BR〉15.4 Concept of Bacterial PHA Synthesis from Syngas〈BR〉15.5 Production of PHA by Acetogens Based on Syngas as Substrate〈BR〉15.6 PHA Production by Rhodospirillum rubrum Grown on Syngas〈BR〉15.7 Synthesis of PHA by Carboxydobacteria Grown on Syngas〈BR〉15.8 PHA Production by CO-Tolerant Hydrogen-Oxidizing Strains on Syngas〈BR〉15.9 Bioprocesses for PHA Production on Syngas〈BR〉15.10 Conclusions and Outlook〈BR〉 References〈/P〉

Additional Edition: Print version : ISBN 9780367275594

Language: English

Keywords: Electronic books. ; Electronic books.

DOI: 10.1201/9780429296611

URL: https://www.taylorfrancis.com/books/9780429296611