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  • 1
    Online Resource
    Online Resource
    Oxford ; : Oxford University Press,
    UID:
    almafu_9959235121002883
    Format: 1 online resource (500 p.)
    Edition: 2nd ed.
    ISBN: 0-19-176873-1 , 1-283-57977-4 , 9786613892225 , 0-19-157532-1
    Content: Opioids have become invaluable in modern medicine but it is essential that they are prescribed with an understanding of the complex pharmacology behind their effectiveness; without this, they will frequently fail to achieve their enormous potential of pain relief, minimal side effects, and improved function. In addition, opioids come with problems, including side effects such as constipation, respiratory depression, and sedation, as well as the potential for substance abuse.Clinicians handling the complex pain problems of cancer patients must incorporate the insight of basic scientists and pha
    Note: Description based upon print version of record. , Contributors; List of abbreviations; 1 Opioid receptors and opioid pharmacodynamics; 2 Opioid pharmacokinetics; 3 Liver disease and exogenous opioid pharmacokinetics; 4 Opioids in renal failure; 5 Codeine; 6 Hydrocodone; 7 Tramadol; 8 Dextropropoxyphene; 9 Morphine; 10 Oxycodone; 11 The lipophilic opioids: fentanyl, alfentanil, sufentanil, and remifentanil; 12 Buprenorphine; 13 Methadone; 14 Hydromorphone; 15 Levorphanol; 16 Diamorphine; 17 Oxymorphone; 18 Choice of opioids and the WHO ladder; 19 Pharmacogenetics and opioids; 20 Opioid rotation; 21 Equi-analgesia. 22 Dosing strategies for acute pain23 Opioid dosing strategies for chronic pain and the management of opioid side effects; 24 Patient-controlled analgesia; 25 Spinal opioids in cancer pain; 26 Opioid poorly responsive pain, physical dependence, tolerance, and opioid-induced hyperalgesia; 27 Opioids in special populations: developing countries; 28 Opioids in special populations: paediatric population; 29 Opioids in the terminal phase; 30 Cancer pain and substance abuse; Index; A; B; C; D; E; F; G; H; I; K; L; M; N; O; P; Q; R; S; T; U; V; W; X. , English
    Additional Edition: ISBN 0-19-923664-X
    Language: English
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