Kooperativer Bibliotheksverbund

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Format: 1 online resource (339 p.)

ISBN: 0-12-801053-3

Content: Volume 6 provides coverage of the mechanisms of regulation of autophagy; intracellular pathogen use of the autophagy mechanism; the role of autophagy in host immunity; and selective autophagy. Attention is given to a number of mechanistic advances in the understanding of regulation, particularly the importance of nutrient availability; microRNAs; and cross-talk with other protein degradation pathways. Intracellular pathogen repurposing of autophagy for pathogenic benefit is also provided, with coverage of Herpesvirus protein modulation of autophagy; the varicella-zoster virus and the maintena

Note: Description based upon print version of record. , Front Cover; Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging; Copyright Page; Dedication; Mitophagy and Biogenesis; Autophagy and Cancer; Contents; Foreword; Preface; Contributors; Abbreviations and Glossary; Autophagy: Volume 1 - Contributions; Autophagy: Volume 2 - Contributions; Autophagy: Volume 3 - Contributions; Autophagy: Volume 4 - Contributions; Autophagy: Volume 5 - Contributions; 1 Introduction to Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 6; Introduction; Specific Functions of Autophagy (A Summary) , Autophagy in Normal Mammalian CellsEndoplasmic Reticulum Stress and Autophagy; Major Types of Autophagies; Macroautophagy (Autophagy); Microautophagy; Chaperone-Mediated Autophagy; Autophagosome Formation; Autophagic Lysosome Reformation; Autophagic Proteins; Abnormal Proteins; Protein Degradation Systems; Beclin 1; Non-Autophagic Functions of Autophagy-Related Proteins; Microtubule-Associated Protein Light Chain 3; Monitoring Autophagy; Reactive Oxygen Species (ROS); Mammalian Target of Rapamycin (mTOR); Role of Autophagy in Tumorigenesis and Cancer; Role of Autophagy in Immunity , Autophagy and SenescenceRole of Autophagy in Viral Defense and Replication; Role of Autophagy in Intracellular Bacterial Infection; Role of Autophagy in Heart Disease; Role of Autophagy in Neurodegenerative Diseases; Cross-Talk between Autophagy and Apoptosis; Autophagy and Ubiquitination; Aggresome: Ubiquitin Proteasome and Autophagy Systems; Autophagy and Necroptosis; Mitochondrial Fusion and Fission; Selective Autophagies; Allophagy; Axonopathy (Neuronal Autophagy); Crinophagy; Glycophagy; Lipophagy; Role of Lipophagy in Alcohol-Induced Liver Disease; Mitophagy; Nucleophagy; Pexophagy , ReticulophagyRibophagy; Xenophagy; Zymophagy; References; I. Autophagy and Molecular Mechanisms; 2 Regulation of Autophagy by Amino Acids; Introduction; Overview of the Insulin-Amino Acid-MTOR Signaling Pathway; Amino Acids, MTOR Signaling and the Regulation of Autophagy; Rag GTPases, v-ATPase, t-RNA Synthetases and Regulation of Autophagy; Glutamate Dehydrogenase and Regulation of Autophagy; Other Pathways Involved in the Amino Acid Regulation of Autophagy; Plasma Membrane Derived Signaling and Regulation of Amino Acid-Dependent Autophagy , Amino Acids, Beclin-1 and the Regulation of AutophagyBeclin-1 Complexes and Autophagy; Regulation of the Activity of the Beclin-1 Complex during Starvation; Conclusion; References; 3 Regulation of Autophagy by Amino Acid Starvation Involving Ca2+; Introduction; Regulation of Autophagy by Amino Acids; Inhibition of Autophagy by Amino Acids; Induction of Autophagy by Amino Acid Starvation; Ca2+-dependent Activation of Autophagy by Amino Acid Starvation; Ca2+/CaMKK-β-dependent Autophagy and Energy; Conclusion; Acknowledgments; References; 4 Regulation of Autophagy by microRNAs; Introduction , Molecular Mechanisms of Autophagy , English

Additional Edition: ISBN 1-322-57607-6

Additional Edition: ISBN 0-12-801032-0

Language: English